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Related Concept Videos

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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Wrist Rigidity Evaluation in Parkinson's Disease: A Scoping Review.

Camille Marques Alves1,2, Andressa Rastrelo Rezende1, Isabela Alves Marques2,3

  • 1Assistive Technology Laboratory (NTA), Faculty of Electrical Engineering, Federal University of Uberlândia, Uberlândia 38400-902, Brazil.

Healthcare (Basel, Switzerland)
|November 11, 2022
PubMed
Summary

Quantitative methods using sensors show promise for assessing Parkinson's disease (PD) wrist rigidity, correlating well with clinical scales. Developing a standardized quantitative approach for clinical use remains a challenge.

Keywords:
Parkinson’s diseaserigidity assessmentwrist rigidity

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Area of Science:

  • Neurology
  • Biomedical Engineering
  • Rehabilitation Medicine

Background:

  • Rigidity is a key Parkinson's disease (PD) symptom impacting daily life, particularly at the wrist.
  • Traditional clinical scales for rigidity assessment suffer from subjectivity and poor reliability.
  • Objective assessment is crucial for effective PD management and recovery monitoring.

Purpose of the Study:

  • To conduct a scope review of methods for assessing wrist rigidity in Parkinson's disease.
  • To evaluate the validity and reliability of existing quantitative assessment techniques.

Main Methods:

  • A systematic literature search was performed across multiple major scientific databases.
  • Included studies utilized instruments like force and inertial sensors for quantitative rigidity assessment.
  • Twenty-eight studies met the inclusion criteria for the review.

Main Results:

  • Quantitative methods using force and inertial sensors demonstrated good correlation with established clinical scales.
  • These sensor-based approaches show potential for objective detection and monitoring of PD-related wrist rigidity.
  • The reviewed methods offer a more reliable alternative to subjective clinical assessments.

Conclusions:

  • Quantitative assessment methods for wrist rigidity in Parkinson's disease are promising and correlate well with clinical evaluations.
  • These methods can aid in the objective detection and monitoring of rigidity.
  • A standardized, widely adopted quantitative method for clinical practice is still needed.