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Pulmonary Rehabilitation in Patients with COVID-19-A Protocol for Systematic Review and Meta-Analysis
Yanan Gao1, Huiming Huang1, Chunxia Ni1
1Faculty of Sport Science, Research Academy of Grand Health, Ningbo University, Ningbo 315211, China.
Insights
This systematic review protocol outlines the first worldwide assessment of pulmonary rehabilitation (PR) for COVID-19 patients. It details methods to evaluate PR
Area of Science:
- Pulmonology and Respiratory Medicine
- Evidence-Based Medicine
- Systematic Review Methodology
Background:
- Pulmonary rehabilitation (PR) is a standard treatment for chronic lung diseases.
- The efficacy of PR specifically for patients recovering from COVID-19 requires systematic investigation.
Purpose of the Study:
- To conduct the first global systematic review and meta-analysis on the effects of pulmonary rehabilitation in COVID-19 patients.
- To establish the impact of PR on key patient outcomes post-COVID-19.
Main Methods:
- Systematic review protocol registered on PROSPERO (CRD42022301418).
- Comprehensive search of five major databases (PubMed, Web of Science, Cochrane, EBSCO, CNKI) from 2019 to July 2022.
- Eligibility criteria defined using the PICOS framework; primary outcomes include pulmonary function, exercise capacity, and quality of life.
- Quantitative data synthesis via narrative synthesis and meta-analysis; qualitative data synthesis through argument and refutational analysis.
Main Results:
- Results will be presented through both meta-analysis and qualitative synthesis.
- This study aims to provide a comprehensive overview of existing evidence.
Conclusions:
- This protocol details the methodology for a novel systematic review and meta-analysis.
- The findings will inform clinical practice regarding the role of pulmonary rehabilitation in COVID-19 recovery.
- Publication in a peer-reviewed journal and broad dissemination are planned.
Introduction:
Pulmonary rehabilitation (PR) is a well-established treatment for patients with chronic lung disease; however, its role in patients with COVID-19 has not been systematically studied. We provide a protocol outlining the methods and analyses that will be used in the systematic review.
Methods:
The methodology of this systematic review protocol has been filed in PROSPERO under the registration number CRD42022301418. Five electronic databases (PubMed, Web of Science, Cochrane Library, EBSCO, and CNKI databases) will be searched from 2019 to 28 July 2022, using pre-determined search terms. Eligibility criteria will be defined using a PICOS framework. Pulmonary function, exercise capacity, and health-related quality of life will be the primary outcomes. Quantitative findings will be narratively synthesized, whilst argument synthesis combined with refutational analysis will be employed to synthesize qualitative data.
Results:
The results will be presented by both meta-analysis and qualitative analysis.
Conclusion:
This protocol describes what will be the first systematic review to conduct a worldwide assessment of the effect of PR in patients with COVID-19. Because this is a systematic review and meta-analysis, no ethical approval is needed. The systematic review and meta-analysis will be published in a peer-reviewed journal and disseminated both electronically and in print.
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