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Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
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Related Experiment Video

Updated: Aug 22, 2025

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
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Shift Work and Early Arterial Stiffness: A Systematic Review.

Waléria D P Gusmão1, Isabele R O M Pureza2, Claudia R C Moreno1

  • 1Department of Health, Life Cycles and Society, School of Public Health, University of Sao Paulo, Sao Paulo 01246-904, Brazil.

International Journal of Environmental Research and Public Health
|November 11, 2022
PubMed
Summary

Shift work

Keywords:
arteriosclerosisnight workshift work

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Area of Science:

  • Occupational Health
  • Cardiovascular Physiology

Background:

  • Shift work, including night shifts, is linked to cardiovascular risks due to circadian rhythm disruption.
  • Arterial stiffness is an emerging cardiovascular risk factor.

Approach:

  • A systematic review analyzed 11 studies on shift work and arterial stiffness, using pulse wave velocity as a key indicator.
  • Keywords included shift work, night work, arteriosclerosis, vascular stiffness, and pulse wave velocity.

Key Points:

  • Findings on arterial stiffness in shift workers were inconsistent: two studies showed higher stiffness, two showed lower, and four found no difference.
  • Two studies linked shorter sleep duration to increased arterial stiffness.
  • One study suggested physical activity may mitigate adverse cardiovascular outcomes in shift workers.

Conclusions:

  • The current evidence is heterogeneous, preventing definitive conclusions about shift work as a risk factor for arterial stiffness.
  • Further research with controlled, longitudinal designs is needed to clarify the relationship between shift work and arterial stiffness.