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Bacteriostatic Poly Ethylene Glycol Plasma Coatings for Orthodontic Titanium Mini-Implants
Juan Carlos Rodriguez-Fernandez1, Francisco Pastor1, Jose Maria Barrera Mora1
1Dept. Ortodoncia, Facultad de Odontología, Universidad de Sevilla, Avicena s/n, 41009 Sevilla, Spain.
Materials (Basel, Switzerland)
|November 11, 2022
Summary
Plasma-treated polyethylene glycol (PEG) coatings create bacteriostatic surfaces on titanium mini-implants, significantly reducing bacterial adhesion and preventing biofilm formation for improved orthodontic anchorage.
Area of Science:
- Biomaterials Science
- Surface Chemistry
- Orthodontics
Background:
- Titanium mini-implants are crucial for orthodontic anchorage but are susceptible to tissue infections.
- Preventing bacterial colonization on implant surfaces is essential for successful treatment outcomes.
Purpose of the Study:
- To develop a bacteriostatic surface on titanium mini-implants using polyethylene glycol (PEG) coating via plasma treatment.
- To evaluate the impact of PEG coating on surface properties, cytocompatibility, and bacterial adhesion.
Main Methods:
- Titanium surfaces were treated with argon and PEG plasma under varying power and time conditions.
- Surface roughness, wettability (contact angle), and chemical composition (XPS) were analyzed.
- Cytocompatibility (fibroblast and osteoblast cells) and bacterial adhesion (Spectrococcus Sanguinis, Lactobacillus Salivarius) were quantified.
Main Results:
- Plasma treatment enhanced surface hydrophilicity without altering roughness.
- PEG coating significantly reduced fibroblast and osteoblast cell adhesion.
- Bacterial adhesion of both S. Sanguinis and L. Salivarius was substantially decreased, with optimal results at 100 W and 30 s PEG treatment.
- Biocompatibility remained high, exceeding 80% in all cases.
Conclusions:
- Plasma-deposited PEG coatings effectively create bacteriostatic titanium surfaces.
- PEG-coated titanium mini-implants show reduced bacterial adhesion and potential for preventing biofilm formation.
- This approach offers a promising strategy to mitigate infection risks associated with orthodontic mini-implants.
