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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Aug 22, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
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Bilateral Optic Neuritis after COVID-19 Vaccination: A Case Report.

Ching-Chih Liu1,2, Wan-Ju Annabelle Lee1,3

  • 1Department of Ophthalmology, Chi Mei Medical Center, Tainan 71004, Taiwan.

Vaccines
|November 11, 2022
PubMed
Summary

Bilateral optic neuritis (ON) is a rare neuro-ophthalmic condition that can occur after the ChAdOx1-S SARS-CoV-2 vaccine. Prompt treatment with corticosteroids is crucial for vision recovery and preventing permanent vision loss.

Keywords:
AZ vaccineCOVID-19ChAdOx1optic neuritisvaccine

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Area of Science:

  • Ophthalmology
  • Neurology
  • Vaccinology

Background:

  • Neuro-ophthalmic events post-vaccination are uncommon, with optic neuritis (ON) being the most frequent. Vaccine-related ON shares similarities with idiopathic ON.
  • Establishing a temporal link between vaccination and ON onset is critical for diagnosis and management.

Observation:

  • A 49-year-old female developed bilateral blurred vision, photophobia, and extraocular pain 14 days post-ChAdOx1-S SARS-CoV-2 vaccination.
  • Ophthalmic examination revealed bilateral disc edema, profound visual field defects, and reduced visual acuity in both eyes.

Findings:

  • The patient presented with acute bilateral optic neuritis following vaccination.
  • Treatment with intravenous and oral corticosteroids led to visual improvement.

Implications:

  • Bilateral ON, though rare, necessitates urgent diagnosis and treatment to prevent irreversible vision loss.
  • Vaccine-induced ON is treatable, but long-term monitoring is advised due to potential associations with other neurological conditions.