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Bilateral Optic Neuritis after COVID-19 Vaccination: A Case Report
Ching-Chih Liu1,2, Wan-Ju Annabelle Lee1,3
1Department of Ophthalmology, Chi Mei Medical Center, Tainan 71004, Taiwan.
Vaccines
|November 11, 2022
Summary
Bilateral optic neuritis (ON) is a rare neuro-ophthalmic condition that can occur after the ChAdOx1-S SARS-CoV-2 vaccine. Prompt treatment with corticosteroids is crucial for vision recovery and preventing permanent vision loss.
Area of Science:
- Ophthalmology
- Neurology
- Vaccinology
Background:
- Neuro-ophthalmic events post-vaccination are uncommon, with optic neuritis (ON) being the most frequent. Vaccine-related ON shares similarities with idiopathic ON.
- Establishing a temporal link between vaccination and ON onset is critical for diagnosis and management.
Observation:
- A 49-year-old female developed bilateral blurred vision, photophobia, and extraocular pain 14 days post-ChAdOx1-S SARS-CoV-2 vaccination.
- Ophthalmic examination revealed bilateral disc edema, profound visual field defects, and reduced visual acuity in both eyes.
Findings:
- The patient presented with acute bilateral optic neuritis following vaccination.
- Treatment with intravenous and oral corticosteroids led to visual improvement.
Implications:
- Bilateral ON, though rare, necessitates urgent diagnosis and treatment to prevent irreversible vision loss.
- Vaccine-induced ON is treatable, but long-term monitoring is advised due to potential associations with other neurological conditions.
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