Related Experiment Video

Updated: Aug 22, 2025

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

3.8K

A case of infective endocarditis in an 8-year-old boy 3 months after transcatheter atrial septal defect closure using

Yuka Toyoshima1, Toshikatsu Tanaka1, Hironori Matsuhisa2

  • 1Department of Cardiology, Kobe Children's Hospital, Kobe, Japan.

Cardiology in the Young
|November 11, 2022
PubMed

Insights

Infective endocarditis is a rare complication after transcatheter closure of atrial septal defects. Insufficient device endothelialization may increase the risk of infection, as seen in a pediatric case report.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Infectious Diseases

Background:

  • Atrial septal defect (ASD) closure is commonly performed using transcatheter devices.
  • Infective endocarditis (IE) is a serious but rare complication following device implantation.
  • The Figulla Flex II occluder is one type of device used for transcatheter ASD closure.

Purpose of the Study:

  • To report a case of infective endocarditis in a child following transcatheter atrial septal defect closure.
  • To investigate the potential role of device endothelialization in the development of infective endocarditis.

Main Methods:

  • Case report of an 8-year-old boy.
  • Transcatheter closure of an atrial septal defect using a Figulla Flex II occluder.
  • Transesophageal echocardiography to visualize device and vegetation.
  • Surgical removal of the device and closure of the ASD.

Main Results:

  • Infective endocarditis occurred 3 months after device implantation.
  • Transesophageal echocardiography revealed vegetation on the left atrial side of the device.
  • The device showed inadequate endothelialization on the left atrial side compared to the right.

Conclusions:

  • Insufficient endothelialization of the transcatheter occluder may be a risk factor for infective endocarditis.
  • Early recognition and management are crucial for patients developing IE post-device closure.
  • Further research into device material and endothelialization is warranted to prevent IE.
Keywords:
ChildFigulla Flex II atrial septal defect occluderatrial septal defectinfective endocarditisvegetation

More Related Videos

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence10:52

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence

Published on: December 23, 2022

3.5K
Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter08:00

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter

Published on: June 15, 2015

14.0K

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
22
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
12
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
21
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
22
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
16
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
26