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Updated: Aug 22, 2025
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Comparing carotid endarterectomy and carotid artery stenting: retrospective single-center analysis
Jeong Su Cho1, Seunghwan Song1, Up Huh1
1Department of Thoracic and Cardiovascular Surgery, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
Insights
Carotid artery stenting (CAS) and carotid endarterectomy (CEA) show similar effectiveness in preventing stroke after elective surgery. Both procedures demonstrated comparable safety profiles and patient outcomes in this comparative study.
Area of Science:
- Vascular Surgery
- Neurology
- Interventional Cardiology
Background:
- Extracranial cerebrovascular diseases account for 20% of ischemic strokes.
- Carotid endarterectomy (CEA) was the standard for carotid artery stenosis until carotid artery stenting (CAS) emerged.
- Comparative trials between CEA and CAS have not definitively established a superior procedure.
Purpose of the Study:
- To compare the efficacy and safety of CAS versus CEA in patients with carotid stenosis.
- To evaluate postoperative complications and patient outcomes for both procedures.
- To contextualize findings within existing literature on carotid revascularization.
Main Methods:
- Single-center retrospective study design.
- Inclusion of patients undergoing elective CAS or CEA between January 2012 and December 2020.
- Analysis of baseline characteristics, postoperative complications (myocardial infarction, cerebral infarction), and mortality.
Main Results:
- 235 patients included: 128 in CAS group, 107 in CEA group.
- No significant differences in 30-day postoperative myocardial infarction (0.8% CAS vs. 0.9% CEA).
- No significant differences in 30-day postoperative cerebral infarction (3.1% CAS vs. 0.9% CEA) or mortality (0.8% CAS vs. 0% CEA).
Conclusions:
- CAS and CEA exhibit equivalent effectiveness in preventing cerebral infarction during elective surgery.
- Both procedures demonstrated comparable safety profiles with no significant differences in postoperative complications.
Background:
Extracranial cerebrovascular diseases represent approximately 20% of ischemic stroke cases. Carotid endarterectomy (CEA) was the gold standard procedure for carotid artery stenosis treatment until the introduction of carotid artery stenting (CAS) in the 1980s. While there have been several multicenter randomized trials comparing CEA and CAS, a more efficacious procedure has not been conclusively distinguished. This study reports the results of CAS versus CEA in patients with symptomatic or asymptomatic carotid stenosis and compares them with those from other studies.
Methods:
This study is a single-center retrospective study and included patients who underwent CAS and CEA as elective surgery between January 2012 and December 2020. The final analysis included patient baseline characteristics, postoperative complications, and patient outcomes.
Results:
The 235 patients included were assigned to the CAS (n=128) and CEA (n=107) groups. Within 30 days postoperatively, no significant differences were noted in myocardial infarction [n=1, 0.8% (CAS); n=1, 0.9% (CEA); P=0.899], cerebral infarction [n=4, 3.1% (CAS); n=1, 0.9% (CEA); P=0.247], and patient mortality [n=1, 0.8% (CAS); n=0, 0% (CEA); P=0.247].
Conclusions:
In elective surgery, CAS and CEA had the same effect of preventing cerebral infarction with no difference in postoperative complications.
