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Related Experiment Video

Updated: Aug 22, 2025

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Published on: December 29, 2015

Nanocalorimetry using microscopic optical wireless integrated circuits.

Conrad L Smart¹, Alejandro J Cortese¹, B J Ramshaw^1,2

¹Laboratory of Atomic and Solid-State Physics, Cornell University, Ithaca, NY 14853.

Proceedings of the National Academy of Sciences of the United States of America

|November 11, 2022

Summary

This summary is machine-generated.

We developed tiny, wireless optical sensors for precise material thermal property measurements. These sensors enable microscale analysis across diverse materials and temperatures, overcoming traditional limitations.

Keywords:

calorimetry microscopic sensor

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Area of Science:

Materials Science
Thermodynamics
Nanotechnology

Background:

Traditional methods for measuring material thermal properties often require larger samples and can be affected by parasitic effects from wiring.
Microscale thermal analysis is crucial for understanding material behavior in advanced applications but faces technical challenges.

Purpose of the Study:

To introduce and validate the use of temperature-sensing optical wireless integrated circuits (OWiCs) for in situ material thermal property measurements.
To demonstrate the versatility and precision of OWiCs across a wide range of materials and sample sizes.

Main Methods:

Utilized microscopic, untethered optical wireless integrated circuits (OWiCs) for in situ calorimetry, thermal conductivity, and thermal diffusivity measurements.
Tested OWiCs on diverse materials including aerogels and metals, with sample masses as low as 100 ng.
Operated sensors over a broad temperature range to capture thermal behavior.

Main Results:

OWiCs successfully measured thermal properties of various materials, from insulators to conductors.
Demonstrated accurate measurements over four orders of magnitude of thermal diffusivity.
Achieved microsecond thermal response times with sensors of ~100 ng mass and 100-μm footprint.
Successfully measured thermodynamic phase transitions in liquid crystal 5CB and gadolinium.

Conclusions:

Optical wireless integrated circuits offer a powerful, non-invasive tool for microscale thermal characterization.
OWiCs significantly advance the ability to measure thermal properties of small samples and diverse materials.
This technology enables new possibilities in materials research, particularly in studying phase transitions and thermal behavior under various conditions.