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Updated: Aug 22, 2025

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
Published on: June 5, 2019
A novel anthropomorphic breathing phantom with a pneumatic MR-safe actuator for tissue deformation studies during MRI
Morgan Wheatley1, Yves De Deene2
1Faculty of Science and Engineering, Macquarie University, Sydney, Australia.
Abstract:
A novel MR-safe anthropomorphic torso phantom with an MR-conditional pneumatic respiration system and inflatable lungs for tissue deformation studies is proposed. The phantom consists of a pair of lungs made from sponges encased in flexible polyurethane. The lung phantom also contains a set of silicone tubes of various diameters to mimic the larger vasculature and airways of the lungs. The lungs are surrounded by a plastic ribcage and immersed in a gelatine hydrogel within a flexible polyurethane skin. A plastic pneumatic pump system was constructed to inflate and deflate the lungs. A fibre optic rotary encoder was constructed to determine the volume of displaced air in the lungs. The pneumatic pump and rotary encoder were constructed of plastic materials to allow placement within the bore of the MR scanner with minimal interaction with the magnetic field. Breath-gated scans and rapid imaging scans (2.5 s per image) were taken of the phantom in the stationary state and during inflation/deflation, and with Cartesian and BLADE k-space sampling. It was found that BLADE shows the least motion artifacts during breathing. This phantom and respiration system shows potential for quality assurance of MRI incorporating breathing corrections and for radiotherapy applications in tracking a moving target.
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