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Updated: Aug 22, 2025

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
Time to surgery and survival in breast cancer
Doyeon An1, Jihye Choi2, Jaebin Lee3
1Department of Health Administration, Graduate School, Kongju National University, Gongju, Republic of Korea.
Background:
This study aimed to investigate the effect of the time from diagnosis to breast cancer surgery on breast cancer patients' prognosis.
Methods:
Of the 1900 patients diagnosed with invasive (stage 1-3) breast cancer who underwent surgery in KUH between 2012 and 2019, 279 patients were enrolled in this study. All patients, including those who received neoadjuvant chemotherapy, were classified as Model 1 subjects, and those who received immediate surgical treatment were classified as Model 2 subjects. We conducted a Cox regression analysis to identify prognostic factors of breast cancer associated with the time from diagnosis to surgery.
Results:
The univariate results indicated a sharp drop in both groups' survival rates when the time to surgery was delayed for more than 8 weeks (Model 1 p = 0.000; Model 2 p = 0.001). In the multivariate analysis, the hazard ratio (HR) of Model 1increased (HR = 6.84, 95% CI 1.06-44.25) in response to a delay in surgery of more than 8 weeks. Smoking and the American Joint Committee on Cancer (AJCC) staging system had a negative effect on breast cancer prognosis, while hormone therapy had a positive effect.
Conclusion:
For all patients, a delay in breast cancer surgery of more than 8 weeks was inversely associated with survival.
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