Related Experiment Video

Updated: Jun 8, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

17.7K

The IPTA Nashville consensus conference on post-transplant lymphoproliferative disorders after solid organ

James D Wilkinson1, Upton Allen2, Michael Green3

  • 1Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Pediatric Transplantation
|November 12, 2022
PubMed

Insights

This report outlines evidence-based guidelines for diagnosing, preventing, and managing post-transplant lymphoproliferative disorders (PTLD) in children undergoing solid organ transplantation. It details the International Pediatric Transplant Association

Area of Science:

  • Pediatric Transplantation
  • Immunology
  • Oncology

Background:

  • Post-transplant lymphoproliferative disorders (PTLD) are serious complications in pediatric solid organ transplantation.
  • Current management strategies require updated, evidence-based guidelines.

Purpose of the Study:

  • To develop consensus guidelines for the diagnosis, prevention, and management of PTLD in pediatric solid organ transplant recipients.
  • To establish standardized approaches for Epstein-Barr viral (EBV) load and biomarker monitoring.

Main Methods:

  • Convened the International Pediatric Transplant Association (IPTA) Consensus Conference.
  • Conducted a critical review of existing literature.
  • Achieved expert consensus on PTLD definitions, diagnosis, prevention, and management.

Main Results:

  • The conference produced comprehensive, evidence-based practice guidelines.
  • Guidelines cover PTLD definitions, diagnostic criteria, preventive strategies, and therapeutic interventions.
  • Specific recommendations for EBV load and biomarker monitoring are included.

Conclusions:

  • The developed guidelines aim to improve outcomes for children with PTLD post-transplantation.
  • Standardized approaches are crucial for effective PTLD management in pediatric solid organ transplantation.
  • This work provides a foundation for future research and clinical practice.

Keywords:
PTLDchildrenpediatric transplantationpediatricspost-transplant lymphoproliferativepractice guidelines

More Related Videos

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

50.2K
International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure05:50

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure

Published on: March 12, 2020

13.8K

Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...