Related Experiment Video
Updated: Aug 22, 2025

08:55
Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
3.1K
Increased intraocular pressure secondary to retinal detachment
K G Sotelo-Monge1, M Muñoz Escudero1, M E Ayala Fuentes1
1Institut Català de Retina, Departamento de Glaucoma, Barcelona, Spain.
Archivos De La Sociedad Espanola De Oftalmologia
|November 12, 2022
Summary
Rhegmatogenous retinal detachment (RRD) can present with elevated intraocular pressure (IOP), contrary to common assumptions. Prompt examination of the anterior chamber and fundus is crucial for diagnosing this association, known as Schwartz-Matsuo Syndrome.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Intraocular Pressure
Background:
- Rhegmatogenous retinal detachment (RRD) is typically associated with low intraocular pressure (IOP).
- Elevated IOP in the presence of RRD is an uncommon presentation.
- The Schwartz-Matsuo Syndrome describes the association between RRD and elevated IOP.
Observation:
- Four male patients presented to the emergency service with symptoms including floaters.
- All patients exhibited mild to moderate anterior chamber inflammation.
- Elevated intraocular pressure (IOP) exceeding 30 mmHg was noted in all cases.
Findings:
- All diagnosed patients had rhegmatogenous retinal detachment (RRD).
- This case series challenges the traditional view of RRD always presenting with low IOP.
- The association of elevated IOP and RRD was observed.
Implications:
- Clinicians must consider RRD in patients presenting with high IOP and anterior chamber inflammation.
- Thorough examination of the anterior chamber and fundus is essential to avoid missed RRD diagnoses.
- Recognizing this association, termed Schwartz-Matsuo Syndrome, facilitates prompt and appropriate management.
Related Concept Videos
Glaucoma: Overview
691
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
691
Open Angle Glaucoma: Treatment
524
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
524
Angle Closure Glaucoma: Treatment
619
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
619
Photoreceptors and Visual Pathways
6.2K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.2K

