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Related Experiment Video

Updated: Aug 22, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

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Pediatric Drug-Induced Sleep Endoscopy.

Erin M Kirkham1

  • 1Department of Otolaryngology - Head & Neck Surgery, The University of Michigan, 1540 East Hospital Dr CW 5-702, SPC 4241, Ann Arbor, MI 48109, USA.

Otolaryngologic Clinics of North America
|November 12, 2022
PubMed
Summary

Drug-induced sleep endoscopy (DISE) aids in diagnosing upper airway obstruction during sleep. Standardizing sedation and scoring protocols is crucial for improving pediatric obstructive sleep apnea treatment outcomes.

Keywords:
DISEObstructive sleep apneaPediatricSleep endoscopyTonsillectomy

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Area of Science:

  • Otolaryngology
  • Sleep Medicine
  • Pediatric Surgery

Background:

  • Drug-induced sleep endoscopy (DISE) evaluates dynamic upper airway obstruction under sedation.
  • It's often used for persistent obstructive sleep apnea after tonsillectomy, with expanding use in non-surgical pediatric cases.
  • Current practices show significant variation in sedation, scoring, and interpretation of DISE findings.

Purpose of the Study:

  • To highlight the expanding clinical indications for pediatric DISE.
  • To identify variations in current DISE practices.
  • To emphasize the need for consensus on anesthetic and scoring protocols.

Main Methods:

  • Review of current practices and literature regarding pediatric DISE.
  • Identification of areas with substantial variation in sedation protocols, scoring methods, and interpretation of findings.
  • Discussion of the impact of these variations on research and clinical application.

Main Results:

  • Pediatric DISE indications are broadening beyond post-tonsillectomy cases to include surgically naïve children.
  • Significant variability exists in sedation techniques, DISE scoring systems, and the application of findings.
  • Lack of standardized protocols hinders rigorous research and validation of DISE's predictive value.

Conclusions:

  • Standardization of anesthetic and scoring protocols for pediatric DISE is essential.
  • Consensus will facilitate robust research to validate the predictive value of DISE for surgical outcomes.
  • Improved standardization will enhance the clinical utility of DISE in pediatric obstructive sleep apnea management.