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Updated: Aug 22, 2025

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Stress perfusion cardiovascular magnetic resonance imaging: a guide for the general cardiologist
Christian Hamilton-Craig1,2, Martin Ugander3,4, John P Greenwood5,6
1Faculty of Medicine and Centre for Advanced Imaging, The University of Queensland, Brisbane, Queensland, Australia c.hamiltoncraig@uq.edu.au.
Insights
Stress cardiovascular magnetic resonance (CMR) is a valuable non-invasive tool for diagnosing ischaemic heart disease (IHD). Despite its proven utility and cost-effectiveness, this imaging technology remains underutilised globally.
Area of Science:
- Cardiovascular Imaging
- Non-invasive Cardiac Diagnostics
Background:
- Stress cardiovascular magnetic resonance (CMR) is an emerging non-invasive imaging technique.
- It assesses myocardial perfusion, wall motion, and cardiac dimensions without ionizing radiation.
Purpose of the Study:
- To highlight the diagnostic and prognostic utility of stress CMR for ischaemic heart disease (IHD).
- To emphasize its role in guiding revascularization decisions and its cost-effectiveness.
- To discuss barriers to its uptake and emerging technological advancements.
Main Methods:
- Utilizes cardiovascular magnetic resonance (CMR) imaging during stress.
- Incorporates assessment of myocardial perfusion, wall motion, and late gadolinium enhancement (LGE).
Main Results:
- Multicentre studies demonstrate high diagnostic and prognostic utility for IHD.
- Stress CMR is effective in guiding invasive angiography and revascularization.
- It is a cost-effective tool across various healthcare settings.
Conclusions:
- Stress CMR is a powerful, underutilised technology for assessing suspected IHD.
- Advancements in automation and AI are increasing its accessibility and standardization.
- The technique is ready for widespread clinical adoption in IHD assessment.
Abstract:
Stress cardiovascular magnetic resonance (CMR) is an emerging non-invasive imaging technique for the assessment of known or suspected ischaemic heart disease (IHD). Stress CMR provides information on myocardial perfusion, wall motion, ventricular dimensions and volumes, as well as late gadolinium enhancement (LGE) scar imaging in a single test without ionising radiation. Data from numerous multicentre randomised studies show high diagnostic and prognostic utility, its efficacy as a gatekeeper to invasive coronary angiography and use for guiding coronary revascularisation decisions. Stress CMR is cost-effective across multiple healthcare settings, yet its uptake and usage varies worldwide and is an underutilised technology. New developments include rapid acquisition protocols, automated quantification of perfusion and myocardial blood flow, and artificial intelligence-aided automated analysis and reporting. Stress CMR is becoming more accessible and standardised around the globe and is ready for 'prime time' use in the non-invasive assessment of patients with suspected IHD.
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