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Comparison of intravenous and inhalation anesthesia on postoperative behavior changes in children undergoing

Vinícius Caldeira Quintão1,2, Ricardo Vieira Carlos1,2, Priscilla Ferreira Neto Cardoso1,2

  • 1Discipline of Anesthesiology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

Paediatric Anaesthesia
|November 13, 2022
PubMed

Insights

Intravenous anesthesia did not reduce postoperative behavior changes in children undergoing ambulatory procedures compared to inhalation anesthesia. However, emergence delirium may increase negative behaviors post-procedure.

Area of Science:

  • Pediatric Anesthesiology
  • Behavioral Science

Background:

  • Behavioral changes after anesthesia are common.
  • Intravenous anesthesia may prevent emergence delirium, but its effect on delayed behavior changes is unknown.

Purpose of the Study:

  • To compare the effectiveness of intravenous anesthesia versus inhalation anesthesia in reducing postoperative behavior changes in children undergoing ambulatory endoscopic procedures.

Main Methods:

  • Randomized, double-blinded controlled trial involving 175 children (aged 1-12 years).
  • Anesthesia maintained with sevoflurane (inhalation) or propofol (intravenous).
  • Behavioral changes assessed using the Posthospitalization Behavior Questionnaire on Days 1, 7, and 14.

Main Results:

  • No significant difference in postoperative behavior changes between intravenous and inhalation anesthesia groups.
  • A moderate correlation was found between emergence delirium and negative postoperative behavior on Day 7.

Conclusions:

  • Intravenous anesthesia did not reduce postoperative behavior changes compared to inhalation anesthesia in this pediatric population.
  • Emergence delirium may be associated with an increased incidence of negative postoperative behavior.
Abstract

Keywords:
anesthesiachild behavioremergence deliriumpostoperative complications

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