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Morphogenesis

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.

Cells Coordinate Growth and Proliferation

Cells Coordinate Growth and Proliferation

Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...

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Related Experiment Video

Updated: Aug 22, 2025

An Analytical Tool that Quantifies Cellular Morphology Changes from Three-dimensional Fluorescence Images

An Analytical Tool that Quantifies Cellular Morphology Changes from Three-dimensional Fluorescence Images

Published on: August 31, 2012

Resolving morphogenesis into quantifiable cell behaviours.

Jeremy B A Green¹

¹Centre for Craniofacial Regeneration and Biology, King's College London, Guy's Campus, London SE1 9RT, UK.

Development (Cambridge, England)

|November 14, 2022

Summary

This summary is machine-generated.

Quantifying cell behaviors like proliferation and division orientation helps understand diverse morphogenesis. This systematic approach reveals the physical mechanisms driving different phenotypes across biology.

Keywords:

Cell behaviours Growth Morphogenesis Quantitative biology

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Area of Science:

Developmental Biology
Cell Biology
Biophysics

Background:

Morphogenesis exhibits vast diversity in phenotypes.
Understanding the physical mechanisms requires quantifying underlying cell behaviors.
A limited set of cell behaviors drives all morphogenetic processes.

Purpose of the Study:

To systematically quantify cell behaviors driving morphogenesis.
To identify the physical mechanisms underlying diverse phenotypes.
To provide a framework for analyzing morphogenetic processes.

Main Methods:

Categorization of fundamental cell behaviors (proliferation, division orientation, rearrangement, matrix production, addition/subtraction, size/shape change).
Discussion of measurement techniques for these behaviors.
Highlighting key examples of morphogenetic processes.

Main Results:

Identified a finite set of cell behaviors that govern morphogenesis.
Demonstrated the possibility of systematically quantifying these behaviors.
Linked specific cell behavior quantifications to distinct phenotypes.

Conclusions:

Systematic quantification of cell behaviors provides insight into physical mechanisms of morphogenesis.
The defined categories of cell behavior are comprehensive.
This framework aids in understanding and predicting developmental processes.