Related Experiment Video
Updated: Aug 22, 2025
04:08
Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
322
Multivariable analysis to determine risk factors associated with abortion in mares
Jessica Roach1, Juan Carlos Arango Sabogal2, Ken Smith3
1J Roach, Comparative Biomedical Sciences, Royal Veterinary College, Hatfield, United Kingdom of Great Britain and Northern Ireland.
Reproduction & Fertility
|November 14, 2022
Summary
Previous abortions, later conception cycles, and multiple fetuses increase abortion risk in Thoroughbreds. However, increasing paternal age may decrease this risk. This study identifies key factors for equine breeding management.
Area of Science:
- Veterinary Medicine
- Reproductive Biology
- Equine Science
Background:
- Equine reproductive efficiency is crucial, with risk factors for early pregnancy loss (EPL) identified.
- Risk factors for equine abortion (pregnancy loss between days 70-300) remain largely unstudied.
- Abortion causes differ from EPL, suggesting distinct risk factors.
Purpose of the Study:
- To identify risk factors associated with abortion in Thoroughbred horses in the UK and Ireland.
- To provide evidence-based data for improving Thoroughbred breeding management and mitigating abortion risk.
Main Methods:
- A retrospective cohort study analyzed data from 2,510 mares over five years.
- Twenty exposure variables were collected and analyzed using a generalized linear mixed model.
- A forward stepwise approach selected variables with a likelihood ratio test p-value < 0.2.
Main Results:
- Two or more prior abortions significantly increased abortion risk (OR 7.91).
- Conception on the second/subsequent estrous cycle (OR 1.84) and multiple conceptuses (OR 1.68) also elevated risk.
- Increasing paternal age was associated with a decreased risk of abortion (OR 0.95).
Conclusions:
- Prior abortions, conception timing, and multiple pregnancies are significant risk factors for Thoroughbred abortion.
- Paternal age may play a protective role against abortion.
- Findings can inform targeted breeding management strategies to reduce equine abortion rates.
Related Concept Videos
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
157
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
157
01:25Multiple Regression
3.1K
Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
3.1K