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Updated: Aug 22, 2025

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Identifying a sphenoid sinus fungus ball using a nomogram model.

Y H Fan1, P W Wu2, Y L Huang3

  • 1Department of Medical Education, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.

Rhinology
|November 14, 2022
PubMed
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This summary is machine-generated.

Sphenoid sinus fungus balls (SSFB) can be differentiated from chronic sphenoid rhinosinusitis using clinical and CT scan features. A new nomogram predicts SSFB probability, aiding diagnosis and preventing complications.

Area of Science:

  • Otolaryngology
  • Radiology
  • Pathology

Background:

  • Sphenoid sinus fungus ball (SSFB) is rare, presenting with non-specific symptoms and potential orbital/intracranial complications.
  • Computed tomography (CT) is crucial for diagnosing sphenoid sinus diseases.
  • Differentiating SSFB from unilateral chronic sphenoid rhinosinusitis (USRS) is important for appropriate management.

Purpose of the Study:

  • To compare clinical and CT features of SSFB and USRS.
  • To identify predictors that differentiate SSFB from USRS.
  • To develop a predictive tool for SSFB diagnosis.

Main Methods:

  • Retrospective review of 66 patients with SSFB and 54 patients with USRS.
  • Evaluation of clinical characteristics and CT scan findings.

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  • Statistical analysis including univariate and multivariate regression.

    • Main Results:

    • Common symptoms in both groups included headache, rhinorrhoea, nasal obstruction, postnasal dripping, and hyposmia.
    • Significant predictors for SSFB included older age, lower white blood cell count, irregular surface, bony dehiscence, lateral wall sclerosis, and intralesional hyperdensity (IH).
    • Older age, irregular surface, and IH were significant in multivariate analysis.

    Conclusions:

    • A nomogram model was developed as a novel preoperative diagnostic tool for SSFB.
    • The nomogram utilizes clinical and CT features to predict SSFB probability.
    • This tool can aid clinicians in reducing ineffective treatment and preventing complications.