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Obstructive sleep apnea: The key for a better asthma control?
Carolina Cisneros1, Gorane Iturricastillo2, Elisa Martínez-Besteiro2
1Servicio de Neumología, Unidad de Asma de Alta Complejidad, Hospital Universitario de La Princesa, Madrid, Spain; Instituto de Investigación La Princesa, Unidad de Asma de Alta Complejidad, Madrid, Spain.
Sleep Medicine
|November 14, 2022
Summary
Continuous positive airway pressure (CPAP) significantly improves asthma control in patients with obstructive sleep apnea (OSA). Most patients experienced better asthma symptom management and tolerated CPAP well.
Area of Science:
- Pulmonology
- Sleep Medicine
- Respiratory Medicine
Background:
- Obstructive sleep apnea (OSA) is a known risk factor for poorly controlled asthma.
- Effective management strategies for comorbid OSA and asthma are crucial for improving patient outcomes.
Purpose of the Study:
- To evaluate the impact of continuous positive airway pressure (CPAP) on symptomatic control in asthma patients diagnosed with OSA.
- To analyze changes in clinical and patient-perceived asthma control after initiating CPAP therapy.
Main Methods:
- A cohort of asthma patients with suspected or confirmed OSA underwent polygraphy.
- Asthma control parameters, including fractional exhaled nitric oxide (FENO) and Asthma Control Test (ACT) scores, were assessed before and after CPAP initiation.
- Patient-reported clinical improvement was also recorded.
Main Results:
- Ninety percent of patients tolerated CPAP, with 54% having severe OSA.
- Asthma control significantly improved post-CPAP, with clinical control rising from 41% good to 70% good (p < 0.001).
- Patient-perceived asthma control, measured by ACT scores, also significantly improved (p < 0.001), with 51.5% reporting clinical improvement.
Conclusions:
- CPAP therapy offers a statistically significant improvement in both clinical and perceived asthma control for patients with OSA.
- The high tolerance rate (90%) and reported clinical benefits suggest CPAP is an effective intervention for this patient population.
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