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Nontunneling Full Thickness Techniques for Neoplasia
Grace E Kim1, Shivangi Kothari2, Uzma D Siddiqui3
1Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, 15841 South Maryland Avenue MC4076, Chicago, IL 60637, USA.
Gastrointestinal Endoscopy Clinics of North America
|November 14, 2022
Summary
Endoscopic full-thickness resection (EFTR) offers a safe and effective alternative for managing locally invasive gastrointestinal cancers, particularly colorectal cancer. This technique provides a viable option when surgical intervention is typically indicated.
Area of Science:
- Gastroenterology and Oncology
- Minimally Invasive Surgical Techniques
Background:
- Colorectal cancer is a leading cause of cancer-related mortality globally and in the US.
- Traditional management for invasive lesions involves surgery, especially for submucosal invasion.
Purpose of the Study:
- To discuss indications, techniques, and limitations of nontunneled endoscopic full-thickness resection (EFTR).
- To review current literature on the outcomes of EFTR for gastrointestinal cancers.
Main Methods:
- Literature review of nontunneled EFTR techniques for gastrointestinal cancers.
- Analysis of outcomes reported in existing studies on EFTR.
Main Results:
- EFTR is emerging as a safe and effective alternative to surgery for localized gastrointestinal cancers.
- The technique is particularly relevant for lesions invading the submucosal layer.
Conclusions:
- Nontunneled EFTR presents a promising endoscopic approach for managing locally invasive gastrointestinal cancers.
- Further research and standardization of EFTR techniques can optimize patient outcomes.

