Related Experiment Video

Updated: Aug 22, 2025

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

14.8K

The future of cardioneuroablation in cardiovascular medicine

Tolga Aksu1, Asad Khan2, Henry Huang2

  • 1Department of Cardiology, Yeditepe University Hospital, Istanbul, Turkey.

Expert Review of Cardiovascular Therapy
|November 14, 2022
PubMed

Insights

Cardioneuroablation shows high success rates for treating vasovagal syncope, especially in younger patients with specific types of VVS. Further research is needed to fully understand its efficacy and patient selection criteria.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Cardioneuroablation is an emerging treatment for vagally mediated bradyarrhythmias.
  • Controversies exist regarding patient selection, safety, efficacy, and procedural endpoints.

Approach:

  • This review summarizes the current role of cardioneuroablation.
  • It discusses controversial issues and evidence from cohort studies, RCTs, and meta-analyses.

Key Points:

  • Cardioneuroablation demonstrates over 90% freedom from syncope recurrence in vasovagal syncope (VVS) patients.
  • Strong recommendations for cardioneuroablation are emerging for specific VVS patient groups (<40 years, cardioinhibitory/mixed types).
  • Sham-controlled trials are suggested to quantify placebo effects in VVS treatment.

Conclusions:

  • Cardioneuroablation offers encouraging medium-term outcomes in carefully selected patients with functional atrioventricular block and sinus bradycardia.
  • However, functional bradycardia is found in a minority of patients with high-grade AV block or sinus node dysfunction.
Abstract

Keywords:
Ablationatrioventricular blockbradycardiaganglionated plexuspacemakersyncope

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