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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Progress in precision therapy in pediatric oncology.

Tara O'Donohue¹, Sameer Farouk Sait, Julia Glade Bender

¹Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Current Opinion in Pediatrics

|November 15, 2022

Summary

Precision medicine and cancer genomics are transforming pediatric oncology. This review explores molecular profiling techniques and targeted therapies to improve diagnosis, risk stratification, and treatment for children with cancer.

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Area of Science:

Pediatric Oncology
Cancer Genomics
Precision Medicine

Background:

The fields of pediatric oncology, precision medicine, and cancer genomics are rapidly advancing.
Novel diagnostic tools are essential for refining cancer diagnoses, patient risk stratification, and treatment decisions.

Conclusions:

Precision medicine offers high-yield clinical scenarios for pediatric cancer treatment.
Ongoing challenges include defining clinical actionability and optimizing trial design.
Expanding access to targeted therapies and validating new tools are crucial for advancing precision oncology.