Related Experiment Video
Updated: Aug 21, 2025

09:53
In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
Published on: June 15, 2018
7.5K
MicroRNA-205-5p: A Potential Therapeutic Target for Combating Unstable Atherogenesis?
Fang Nie1, Xuejing Hao1, Yancai Han2
1Department of Cardiology, Liaocheng Third People's Hospital (Liaocheng Key Laboratory of Cardiovascular Disease Diagnosis and Treatment), Liaocheng, 252000, People's Republic of China.
Cardiovascular Drugs and Therapy
|November 15, 2022
Abstract
No abstract available in PubMed .
Related Concept Videos
MicroRNAs
3.1K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
3.1K
Atherosclerosis III: Management
19
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
19

