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Connectivity-Based Brain Parcellation for Parkinson's Disease.

Yu Li, Aiping Liu, Liangyong Li

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    |November 15, 2022
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    Connectivity-based parcellation (CBP) advances brain mapping for Parkinson's Disease (PD) and deep brain stimulation (DBS) surgery. Challenges remain in PD population heterogeneity for robust atlases.

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    Area of Science:

    • Neuroimaging
    • Computational Neuroscience
    • Neurology

    Background:

    • Connectivity-based parcellation (CBP) rapidly advances cerebral topographic organization understanding.
    • CBP aids in studying human brain development and neurological disorders like Parkinson's Disease (PD).
    • CBP offers promising methods for guiding deep brain stimulation (DBS) electrode placement.

    Conclusions:

    • CBP is a valuable tool for PD research and surgical planning, but limitations exist.
    • Future research should address PD heterogeneity and explore multi-modal approaches for improved parcellation.
    • Enhanced CBP methods are crucial for advancing PD understanding and optimizing DBS surgical planning.