Stability improvement of carboxymethyl cellulose/chitosan complex beads by thermal treatment

Carboxymethyl cellulose (CMC) and chitosan (CHI) are two well-known natural polymer derivatives, as such the CMC@CHI complex beads fulfill many requirements for bio-related and safety-required applications. However, poor mechanical properties of CMC@CHI beads hinder their applications. We managed to improve the beads stability by a simple thermal treatment during the bead preparation. The effects of temperature, changing from 25 °C to 75 °C, on the stability of the formed beads were investigated. The morphology, diameter, shell thickness and structure of the beads treated at different temperature were analyzed using SEM, XPS and FTIR. The mechanical test and swelling experiments showed that the thermal treatment enhanced the bead's ability to withstand pressure and swelling. The beads treated at 75 °C showed the best pressure resistance, while the beads treated at 55 °C exhibited the highest swelling capability without losing integrity. This method is convenient to implement, not only improves the stability, but also controls the swelling capacity and mechanical properties of the beads, which are important for their potential applications in adsorption and controlled release. More importantly, this work offered insights on the effects of thermal treatment on the complexation process of the two polysaccharide molecular chains.