Enhanced stent visualization system for percutaneous coronary intervention in patients with chronic kidney disease:
Yunpeng Tian1, Xiangdong Zhao1, Yang Yang1
1Department of Cardiology, Tianjin First Central Hospital, Tianjin, China.
Insights
Enhanced stent visualization (ESV) systems significantly reduce contrast media volume and radiation dose during percutaneous coronary intervention (PCI). This is particularly beneficial for patients with chronic kidney disease (CKD), potentially lowering renal impairment risk.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Nephrology
Background:
- Coronary heart disease (CHD) and chronic kidney disease (CKD) share pathological pathways.
- Iodinated contrast media used in angiography can cause contrast-associated acute kidney injury (CA-AKI), worsening CKD.
- The impact of enhanced stent visualization (ESV) systems on contrast media and radiation dose in PCI, especially for CKD patients, requires further investigation.
Purpose of the Study:
- To evaluate the effect of ESV systems on contrast media volume and radiation dose during percutaneous coronary intervention (PCI).
- To assess the benefits of ESV systems in patients with chronic kidney disease (CKD) undergoing PCI.
Main Methods:
- Retrospective analysis of 124 patients with acute coronary syndrome undergoing PCI.
- Patients were divided into an ESV-guided group (n=64) and an angiography-guided group (n=60).
- Procedural parameters including contrast media volume, radiation exposure (Air Kerma and Dose Area Product), and procedure time were recorded and analyzed.
Main Results:
- The ESV-guided group showed a significant reduction in contrast media volume (132.6 ± 22.3 ml vs. 174.7 ± 29.6 ml, p=0.0001).
- Radiation exposure was significantly lower in the ESV group (Air Kerma: p=0.002, Dose Area Product: p=0.030).
- Procedure time was also reduced in the ESV group (53.06 ± 21.20 min vs. 72.00 ± 30.55 min, p=0.01).
Conclusions:
- Enhanced stent visualization (ESV) systems are associated with reduced contrast media usage, radiation dose, and procedure time during PCI.
- Subgroup analysis confirmed these benefits in patients with CKD.
- ESV-guided PCI offers potential benefits for reducing renal impairment and mitigating CKD progression in CHD patients with CKD.
Objective:
We aimed to assess the impact of using enhanced stent visualization (ESV) systems on contrast media volume and radiation dose in percutaneous coronary intervention (PCI), especially for patients with chronic kidney disease (CKD).
Background:
Coronary heart disease (CHD) is associated with chronic kidney disease (CKD), as they share a similar pathological pathway. In addition, the iodinated contrast media used for angiography is a risk factor for contrast-associated acute kidney injury (CA-AKI), which could aggravate the progression of CKD. We hypothesized that ESV systems have the potential to reduce the use of contrast media as well as the radiation dose; however, few studies have reported the impact on contrast media with the use of ESV systems.
Methods:
We retrospectively collected 124 patients with acute coronary syndrome who underwent PCI from May 2020 to July 2021. The patients were divided into the ESV-guided group (n = 64) and angiography-guided group (n = 60). Procedural parameters, including contrast media volume, radiation exposure (in Air Kerma-AK and Dose Area Product-DAP), number of cines, cine frames, fluoroscopy and procedure time, were recorded and analysed.
Results:
The groups were comparable regarding the patient characteristics. There was a significant reduction in contrast media volume (174.7 ± 29.6 ml vs.132.6 ± 22.3 ml, p = 0.0001), radiation exposure (776 (499 - 1200) mGy vs. 1065 (791 - 1603) mGy, p = 0.002 in AK; 43 (37 - 73) Gycm2 vs. 80 (64 - 133) Gycm2, p = 0.030 in DAP) and procedure time (53.06 ± 21.20 min vs. 72.00 ± 30.55 min, p = 0.01) with the use of ESV systems. Similar results were observed in the subgroup analysis for the patients with CKD.
Conclusion:
This study suggested that the use of ESV is associated with reduced contrast media usage, radiation dose and procedure time during PCI. The same results were observed in a subgroup analysis in patients with CKD, and this shows that ESV-guided PCI has the potential to reduce renal impairment and mitigate the progression of CKD for those CHD patients with CKD.
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