Jove
Visualize
Contact Us

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

AI-based selection of tumor regions for genomic profiling in neuropathology.

Neuro-oncology advances·2026
Same journal

Postsurgical detection of glioma recurrence using MRI radiomics.

Neuro-oncology advances·2026
Same journal

Repurposing salmon calcitonin for glioblastoma treatment: Targeting Yes-associated Protein (YAP)/ Transcriptional co‑activator with PDZ‑binding motif (TAZ) via hippo pathway activation.

Neuro-oncology advances·2026
Same journal

Emerging blood-based biomarkers for the detection of parenchymal brain metastasis: Current progress and future perspectives.

Neuro-oncology advances·2026
Same journal

Defining rapid early progression in glioblastoma-A volumetric approach.

Neuro-oncology advances·2026
Same journal

Medulloblastoma immune microenvironment resembles early brain development and reveals novel basophil- B cell- associated signatures.

Neuro-oncology advances·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Aug 21, 2025

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples
08:49

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Published on: January 13, 2023

2.0K

Liquid biopsy-from bench to bedside.

Amitava Ray1, Tarang K Vohra2

  • 1Senior Consultant Neurosurgeon, Department of Neurosciences, Apollo Health City and Apollo Secunderabad, Hyderabad 500089, Telangana, India.

Neuro-Oncology Advances
|November 16, 2022
PubMed
Summary
This summary is machine-generated.

Liquid biopsy (LB) analyzes biomarkers in biofluids for Central Nervous System (CNS) tumor management. This review explores LB

Keywords:
brain tumorsliquid biopsy

More Related Videos

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications
05:26

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

Published on: September 16, 2022

4.1K
Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients
08:25

Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients

Published on: September 9, 2020

11.2K

Related Experiment Videos

Last Updated: Aug 21, 2025

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples
08:49

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Published on: January 13, 2023

2.0K
A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications
05:26

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

Published on: September 16, 2022

4.1K
Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients
08:25

Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients

Published on: September 9, 2020

11.2K

Area of Science:

  • Neuro-oncology
  • Molecular diagnostics
  • Biomarker research

Background:

  • Molecular markers are crucial for Central Nervous System (CNS) tumor management.
  • Somatic mutations in CNS tumors can be detected in biofluids like serum and cerebrospinal fluid (CSF).
  • Liquid biopsy (LB) is a technique sampling these biofluids for tumor-derived biomarkers.

Purpose of the Study:

  • To review the current status of liquid biopsy (LB) research in CNS tumors.
  • To highlight the potential applications and challenges of LB in neuro-oncology.
  • To provide a comprehensive overview of LB as a diagnostic and prognostic tool.

Main Methods:

  • Review of current literature on liquid biopsy in CNS tumors.
  • Analysis of various biomarkers detectable in biofluids, including circulating tumor cells (CTCs), cell-free DNA (cf/ctDNA), circulating cell-free microRNAs (cfmiRNAs), extracellular vesicles (EVs), proteins, and tumor-educated platelets.
  • Discussion of the established role of LB in other malignancies and its emerging importance in CNS oncology.

Main Results:

  • Liquid biopsy offers a minimally invasive approach to detect and monitor CNS tumors.
  • Biomarkers such as cf/ctDNA and CTCs show promise for early detection, prognosis, and treatment response assessment.
  • LB techniques are evolving, with ongoing research to overcome existing limitations.

Conclusions:

  • Liquid biopsy is a rapidly advancing field with significant potential in the management of CNS tumors.
  • Further research is needed to optimize LB techniques and validate biomarkers for clinical application.
  • LB is expected to become an indispensable tool in neuro-oncology, complementing traditional diagnostic methods.