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Published on: March 15, 2024
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Advances in penile-sparing surgical approaches
Karl H Pang1, Hussain M Alnajjar1, Asif Muneer1,2,3
1Institute of Andrology, University College London Hospital, University College London Hospitals NHS Foundation Trust, London, UK.
Asian Journal of Urology
|November 16, 2022
Summary
Penile-preserving surgery (PPS) offers a viable treatment for penile cancer (PeCa), maintaining oncological control while preserving urinary and sexual functions. This approach is standard for distal tumors not invading the corpus cavernosa.
Area of Science:
- Oncology
- Urology
- Surgical Oncology
Background:
- Penile cancer (PeCa) is a rare malignancy, representing 0.4% of male cancers globally.
- Surgical treatment for PeCa is determined by tumor location and invasion depth.
Purpose of the Study:
- To review the oncological and functional outcomes of penile-preserving surgery (PPS) for PeCa.
- To evaluate different penile-sparing surgical techniques and their results.
Main Methods:
- A comprehensive PubMed search was conducted up to July 2021.
- A narrative review of penile-sparing approaches for PeCa was performed.
Main Results:
- Penile-preserving surgery (PPS) is the standard of care for distal PeCa not involving the corpus cavernosa in specialized centers.
- Treatment options include laser therapy, glans resurfacing, and wide local excision for superficial lesions.
- Glansectomy is necessary for lesions invading the corpus spongiosum.
Conclusions:
- Penile-preserving surgery (PPS) aims to preserve both urinary and sexual function in penile cancer (PeCa) patients.
- These functional outcomes can be achieved without compromising oncological results.

