Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

ADOXI-PLOT: a computer program for plotting pedigrees illustrating autosomal dominant and X-linked inheritance.

K Fenger, S A Sørensen

    Computer Methods and Programs in Biomedicine
    |August 1, 1986
    PubMed
    Summary

    A new FORTRAN program, ADOXI-PLOT, generates pedigrees for genetic inheritance studies. It uses distinct symbols and adapts layout for family size, aiding genetic analysis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Integrating EM and Patch-seq data: Synaptic connectivity and target specificity of predicted Sst transcriptomic types.

    bioRxiv : the preprint server for biology·2023
    Same author

    The Danish HD Registry-a nationwide family registry of HD families in Denmark.

    Clinical genetics·2017
    Same author

    4p16.3 haplotype modifying age at onset of Huntington disease.

    Clinical genetics·2009
    Same author

    Impaired glucose tolerance in the R6/1 transgenic mouse model of Huntington's disease.

    Journal of neuroendocrinology·2007
    Same author

    Double-blind crossover trial of gabapentin in SPG4-linked hereditary spastic paraplegia.

    European journal of neurology·2007
    Same author

    Hereditary spastic paraplegia with cerebellar ataxia: a complex phenotype associated with a new SPG4 gene mutation.

    European journal of neurology·2005

    Area of Science:

    • Genetics
    • Bioinformatics
    • Computational Biology

    Background:

    • Genetic studies require clear visualization of family relationships and inheritance patterns.
    • Existing methods for pedigree plotting may lack flexibility or automation.

    Purpose of the Study:

    • To develop an automated plotting program for visualizing genetic inheritance patterns.
    • To create a versatile tool for constructing pedigrees in genetic research.

    Main Methods:

    • Development of a FORTRAN program named ADOXI-PLOT (Autosomal Dominant Or X-linked Inheritance Plot).
    • Implementation of distinct symbols for characterizing family members.
    • Algorithmic adaptation of pedigree appearance (rectangular or circular) based on family size.

    Related Experiment Videos

    Main Results:

    • ADOXI-PLOT successfully generates visually distinct pedigrees.
    • The program automatically adjusts pedigree layout for optimal representation.
    • Input data can be provided directly or from a family register.

    Conclusions:

    • ADOXI-PLOT offers an efficient and automated solution for pedigree plotting in genetic research.
    • The program's flexibility enhances its utility for diverse genetic studies.
    • Integration with family registers streamlines data input for plotting.