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Author Spotlight: Cutting-Edge Robotic Heller Myotomy Protocol for Treatment of Achalasia
Published on: February 16, 2024
Comparative Analysis of Heller Myotomy With Dor Versus Toupet Fundoplication for Achalasia Cardia
Sunita Suman1, Vaibhav K Varshney1, Subhash Soni1
1Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, IND.
Insights
Heller myotomy with Toupet fundoplication (HM+TF) showed a trend toward lower failure rates and better esophageal function compared to Dor fundoplication (HM+DF) in achalasia cardia patients. Long-term studies are needed to confirm these findings.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Esophageal Motility Disorders
Background:
- Heller myotomy (HM) with partial fundoplication is standard for achalasia cardia.
- The optimal type of partial fundoplication remains debated.
Purpose of the Study:
- To compare Dor fundoplication (DF) versus Toupet fundoplication (TF) after HM.
- To evaluate subjective and objective outcomes in achalasia patients.
Main Methods:
- Prospective comparative study of 30 achalasia patients undergoing HM with either DF (n=15) or TF (n=15).
- Assessment included Eckardt score, quality of life, 24-hour pH monitoring, and high-resolution manometry (HRM) at 1-year follow-up.
Main Results:
- No significant differences in baseline characteristics, hospital stay, or complications.
- HM+TF showed a trend towards lower failure rates (0% vs 27%) and improved esophagogastric junction (EGJ) relaxation on HRM (p=0.058).
- Similar rates of pathological acid reflux were observed between groups.
Conclusions:
- HM+TF demonstrated a trend towards better outcomes than HM+DF in achalasia patients.
- Further long-term research is necessary to validate these findings using robust criteria.
Abstract:
Background Heller myotomy (HM) with partial fundoplication is the standard of care for achalasia cardia. However, the choice of partial fundoplication is controversial. In this study, we compared both types of fundoplication concerning subjective and objective parameters. Methodology This prospective comparative study comprised a total of 30 consecutive patients who underwent laparoscopic/robotic HM with either Dor fundoplication (DF) (n = 15) or Toupet fundoplication (TF) (n = 15). Preoperative baseline characteristics, intraoperative details, and postoperative complications were recorded. Patients were followed with Eckardt score, quality of life-related scores, 24-hour pH study, and high-resolution manometry (HRM) at the one-year follow-up. Results There was no significant difference between the two groups regarding preoperative baseline parameters, length of hospital stay, and postoperative complications. The HM+DF group had four (27%) patients with recurrence/failure with none in the HM+TF, but it was not significant (p = 0.79). Symptom scores were similar between the groups at six and 12 months of follow-up. One patient in the HM+DF group and two in the HM+TF group had significant pathological acid reflux (p = 0.483). On HRM, HM+TF showed a trend toward significance in terms of esophagogastric junction (EGJ) relaxation (p = 0.058) with a non-significant difference in median integrated relaxation pressure (p = 0.081). Conclusions The study showed a trend toward lower failure rates and improved EGJ relaxation with similar reflux rates in patients who underwent HM+TF compared to HM+DF. However, long-term follow-up is required to validate our findings with well-defined subjective and objective criteria.
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