Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

522
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
522
Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

3.9K
Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
3.9K
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors01:28

Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

229
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
229
Angina IV: Management01:26

Angina IV: Management

15
IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
15
Infertility in Males01:23

Infertility in Males

316
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
316
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

19
Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
19

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Health Professionals' Approaches to Support Patient Diversity in the Assessment of Vaginismus: A Critical Feminist Qualitative Study for Inclusive Care.

Healthcare (Basel, Switzerland)·2026
Same author

The interrelationship between women's help-seeking experiences for vaginismus and their sense of self: a qualitative study and abductive analysis.

Health psychology and behavioral medicine·2024
Same author

Sexual dysfunction: a study on learning experience of Australian medical students.

Sexual health·2024
Same author

Urological Society of Australia and New Zealand (USANZ) and Australasian Chapter of Sexual Health Medicine (AChSHM) for the Royal Australasian College of Physicians (RACP) clinical guidelines on the management of erectile dysfunction.

The Medical journal of Australia·2022
Same author

Sexual Function in Men Living With a Fontan Circulation.

Frontiers in pediatrics·2021
Same author

Sexual dysfunctions and sex therapy: The role of a general practitioner.

Australian journal of general practice·2020
Same journal

Dual antihypertensive fixed-dose combinations approved for first-line use on the Pharmaceutical Benefits Scheme.

Australian prescriber·2026
Same journal

Capivasertib for locally advanced or metastatic breast cancer.

Australian prescriber·2026
Same journal

Diagnosis and management of irritable bowel syndrome.

Australian prescriber·2026
Same journal

Stopping antidepressants: when and how.

Australian prescriber·2026
Same journal

Emergency contraception: an overview.

Australian prescriber·2026
Same journal

Sodium valproate: balancing benefits and risks especially in people of childbearing potential.

Australian prescriber·2026
See all related articles

Related Experiment Video

Updated: Aug 21, 2025

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation
03:51

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation

Published on: December 8, 2023

3.0K

Erectile dysfunction: causes, assessment and management options.

Michael Lowy1,2, Vijayasarathi Ramanathan1,2

  • 1Double Bay, Sydney.

Australian Prescriber
|November 16, 2022
PubMed
Summary
This summary is machine-generated.

Erectile dysfunction (ED) management involves lifestyle changes, medical treatments like phosphodiesterase-5 inhibitors, and therapy. Clear instructions are vital for effective treatment, especially for those with severe conditions or psychological factors impacting response.

Keywords:
erectile dysfunctionimpotencephosphodiesterase-5 inhibitors

More Related Videos

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
02:21

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Published on: March 15, 2024

762
Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

3.5K

Related Experiment Videos

Last Updated: Aug 21, 2025

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation
03:51

Author Spotlight: Advanced Treatment of Seminal Duct Blockage Employing Endoscopy-Mediated Semen Channel Refluviation

Published on: December 8, 2023

3.0K
Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
02:21

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Published on: March 15, 2024

762
Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

3.5K

Area of Science:

  • Urology
  • Andrology
  • Sexual Medicine

Background:

  • Erectile dysfunction (ED) is a prevalent male sexual health concern.
  • Diagnosis typically relies on comprehensive patient history and physical examination.
  • Effective management requires a multifaceted approach.

Purpose of the Study:

  • To outline the diagnostic and management strategies for erectile dysfunction.
  • To emphasize the role of multimodal treatment in improving patient outcomes.
  • To highlight factors influencing treatment response, particularly to oral phosphodiesterase-5 inhibitors.

Main Methods:

  • Review of current diagnostic criteria and clinical guidelines for ED.
  • Analysis of established treatment modalities including lifestyle modifications, pharmacotherapy, and psychosexual interventions.
  • Identification of patient-specific factors affecting therapeutic efficacy.

Main Results:

  • Multimodal management, including lifestyle changes, medical treatments, and psychosexual therapy, offers significant benefits for men with ED.
  • Oral phosphodiesterase-5 inhibitors are a common first-line medical treatment.
  • Patient factors such as severe vascular disease, prior pelvic surgery, anxiety, and unrealistic expectations can impede treatment success.

Conclusions:

  • A comprehensive, individualized approach is essential for managing erectile dysfunction effectively.
  • Optimizing treatment outcomes requires clear patient education and realistic expectation setting.
  • Addressing underlying physiological and psychological factors is crucial for successful ED management.