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Updated: Aug 21, 2025

Glucose Uptake Measurement and Response to Insulin Stimulation in In Vitro Cultured Human Primary Myotubes
Published on: June 25, 2017
Dynamics of a glucose-insulin model
1College of Science, Xi'an Polytechnic University, Xi'an, People's Republic of China.
Abstract:
Diabetes mellitus is a noncommunicable disease, which is a serious threat to human health around the world. In this paper, we propose a simple glucose-insulin model with Michaelis-Menten function as insulin degradation rate to mimic the pathogenic mechanism of diabetes. By theoretical analysis, a unique positive equilibrium of model exists and it is globally asymptotically stable. The four strategies are designed for diabetes patients based on the sensitivity of parameters, including insulin injection and medicine treatments. Numerical simulations are given to support the theoretical results.
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