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Updated: Aug 21, 2025

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
Published on: March 11, 2017
Interaction between hepatokines and metabolic diseases.
Jia-Qi Liang1, Chang Liu1, Wen-Xiang Zhang1
1College of Life Sciences, China Pharmaceutical University, Nanjing 211198, China.
Hepatokines, secreted by the liver, are crucial in regulating metabolism. Understanding their role in metabolic diseases offers new therapeutic strategies for conditions like obesity and insulin resistance.
Area of Science:
- Metabolic biology and endocrinology.
- Liver physiology and disease.
Background:
- Metabolic diseases encompass conditions like obesity, insulin resistance, and hypertension.
- The liver is a central organ regulating systemic glucose and lipid metabolism.
- Hepatokines are liver-secreted proteins influencing metabolic homeostasis.
Conclusions:
- Hepatokines represent a significant area for therapeutic intervention in metabolic diseases.
- Further research is essential to elucidate the precise mechanisms of hepatokines in maintaining metabolic balance.
- Targeting hepatokines may offer novel strategies for treating metabolic dysfunction.
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