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Telmisartan-induced angioedema: A rare clinical finding
Nitesh Kumar1, Madhu Kiran2, Kapil Gupta3
1Department of Emergency Medicine, AIIMS Jodhpur, Rajasthan, India.
Journal of Family Medicine and Primary Care
|November 17, 2022
Summary
A rare case of angioedema, a dangerous swelling, occurred in a patient taking Telmisartan for hypertension. Discontinuing the medication led to symptom resolution, highlighting a potential adverse effect.
Area of Science:
- Cardiology
- Pharmacology
- Emergency Medicine
Background:
- Angioedema is a rare but serious adverse effect of certain medications.
- Angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are known culprits.
- Hypertension management often involves these drug classes.
Observation:
- A 52-year-old female presented with facial swelling and dysphagia.
- She was recently prescribed Telmisartan and Amlodipine for hypertension.
- Symptoms developed over three days.
Findings:
- Discontinuation of Telmisartan and Amlodipine resulted in symptom improvement within five days.
- This case suggests Telmisartan, an ARB, may induce angioedema.
- Angioedema induced by ARBs is an uncommon presentation.
Implications:
- Clinicians should consider ARBs as a potential cause of angioedema.
- Prompt medication review and discontinuation are crucial for managing drug-induced angioedema.
- Further research into the specific mechanisms of ARB-induced angioedema is warranted.
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