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Primary hepatic angiosarcoma: A case report.

Jian Wang1, Li-Tao Sun2

  • 1Cancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.

World Journal of Clinical Cases
|November 17, 2022
PubMed
Summary
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Primary hepatic angiosarcoma (PHA) is a rare liver cancer. Contrast-enhanced ultrasound (CEUS) shows characteristic liver nodules and aids biopsy, improving diagnosis of this challenging vascular tumor.

Area of Science:

  • Hepatology
  • Vascular Oncology
  • Diagnostic Imaging

Background:

  • Primary hepatic angiosarcoma (PHA) is a rare vascular endothelial malignancy.
  • Clinical presentation and standard diagnostics for PHA often lack specificity.
  • This case highlights diagnostic challenges and imaging features of PHA.

Observation:

  • A 75-year-old woman presented with nonspecific abdominal pain and multiple liver lesions on initial imaging.
  • Contrast-enhanced ultrasound (CEUS) revealed suspicious hyperechoic nodules.
  • CT and MRI showed nonspecific findings, mimicking other liver pathologies.

Findings:

  • Laboratory results included decreased platelets and elevated D-dimer.
  • Histopathology confirmed primary hepatic angiosarcoma.
Keywords:
Case reportImagingPathologyPrimary hepatic angiosarcomaUltrasonic diagnosis

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  • CEUS demonstrated characteristic vascular patterns suggestive of PHA.
  • Implications:

    • CEUS offers crucial diagnostic clues for primary hepatic angiosarcoma.
    • Utilizing CEUS can enhance the diagnostic yield of liver biopsies.
    • Early and accurate diagnosis of PHA is critical for patient management.