Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Management of Insomnia01:19

Management of Insomnia

307
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
307
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

1.5K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.5K
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

264
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
264
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

336
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
336
Narcolepsy01:07

Narcolepsy

179
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
179
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

226
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
226

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polygenic Risk for Insomnia in Relation to Sleep Disturbance and Psychiatric Characteristics in Youth with Mood Disorders.

Journal of child and adolescent psychopharmacology·2026
Same author

Matchmaking: trends in the nrmp sleep match.

ATS scholar·2026
Same author

Depressive symptoms, but not OSA severity, are associated with general fatigue in myasthenia gravis.

Sleep medicine·2026
Same author

Redefining Obstructive Sleep Apnea: Multidimensional Phenotyping Beyond the Apnea-Hypopnea Index.

Pathophysiology : the official journal of the International Society for Pathophysiology·2026
Same author

Feasibility of home testing to detect undiagnosed obstructive sleep apnea in late life depression.

Sleep medicine·2026
Same author

Evaluating the Role of Inpatient Sleep Studies in Hospitalized Adults in Relation to One-Year Mortality and Healthcare Utilization: A Population-Based Cohort Study.

Annals of the American Thoracic Society·2026

Related Experiment Video

Updated: Aug 21, 2025

Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

7.7K

The mobile sleep medicine model in neurologic practice: Rationale and application.

Mark I Boulos1,2,3, Luqi Chi4, Oleg Y Chernyshev5,6

  • 1Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

Frontiers in Neurology
|November 17, 2022
PubMed
Summary
This summary is machine-generated.

Undiagnosed obstructive sleep apnea (OSA) significantly impacts neurological patients. An integrated Mobile Sleep Medicine (iMSM) model improves access to screening, testing, and treatment for better patient outcomes.

Keywords:
ambulatory sleep testingcognitive impairmenthome sleep apnea test (HSAT)mobile sleep medicineneuromuscular conditionsscreeningsleep-disordered breathingstroke

More Related Videos

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.4K
Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
08:58

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice

Published on: June 19, 2019

9.8K

Related Experiment Videos

Last Updated: Aug 21, 2025

Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

7.7K
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.4K
Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
08:58

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice

Published on: June 19, 2019

9.8K

Area of Science:

  • Neurology
  • Sleep Medicine
  • Public Health

Background:

  • Undiagnosed obstructive sleep apnea (OSA) is common in neurology patients, increasing morbidity and mortality.
  • OSA causes neurocognitive, cardiovascular, and cerebrovascular impairments, affecting sleep quality.
  • Limited access to sleep medicine care hinders timely OSA treatment and risk reduction.

Purpose of the Study:

  • To highlight the importance of systematic OSA and hypoventilation/hypoxemia syndromes (HHS) management in neurological conditions.
  • To introduce and justify the integrated Mobile Sleep Medicine (iMSM) care model.
  • To demonstrate iMSM's utility in neurological practice for OSA and HHS screening, testing, and management.

Main Methods:

  • Discussion of systematic screening, testing, and management protocols for OSA and HHS.
  • Introduction of the iMSM model, featuring a Mobile Sleep Medicine Unit.
  • Description of the three-level operational protocol for iMSM.

Main Results:

  • The iMSM model is designed as a patient-centered, outcome-based program.
  • iMSM aims to enhance access to OSA management across all healthcare levels.
  • The model facilitates efficient screening, timely testing, and coordinated follow-up care.

Conclusions:

  • The iMSM model offers an innovative approach to patient-centered sleep medicine care.
  • Adoption of the iMSM model can benefit all stakeholders in clinical sleep medicine services.
  • iMSM improves access and efficiency in managing OSA and related conditions in neurological practice.