Malignant Left Ventricular Outflow Tract Obstruction: A Reason to Operate?
Anna B Grimaldo1, Keith McConn1, Joseph J Maleszewski2
1Alix School of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
JACC. Case Reports
|November 17, 2022
Summary
High-grade synovial sarcoma can spread to the heart, causing outflow tract obstruction and mitral regurgitation. Surgical mitral valve replacement effectively treated these cardiac complications in one patient.
Area of Science:
- Cardiology
- Oncology
- Cardiac Surgery
Background:
- High-grade synovial sarcoma is a rare soft tissue malignancy.
- Cardiac involvement by sarcoma is uncommon and can present with significant hemodynamic compromise.
Observation:
- A 57-year-old male patient with high-grade synovial sarcoma developed intracardiac tumor.
- The tumor caused dynamic left ventricular outflow tract obstruction and severe mitral regurgitation.
Findings:
- The patient underwent successful mitral valve replacement surgery.
- At 1-year follow-up, the patient remained asymptomatic from a cardiovascular perspective.
Implications:
- This case highlights the importance of considering cardiac involvement in advanced sarcomas.
- Surgical intervention for intracardiac tumors can lead to favorable outcomes.
- Mitral valve replacement is a viable option for managing sarcoma-induced valvular dysfunction.
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