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Evolution of focal choroidal excavation in ABCA4-related retinopathy
Matthew D Benson1, Carly B Feldman1, Wadih M Zein1
1Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, United States.
Purpose:
To report long-term evolution of unilateral focal choroidal excavation in a patient with ABCA4-related retinopathy.
Observations:
A 51-year-old female with ABCA4-related retinopathy developed a small juxtafoveal defect in Bruch's membrane in a region of macular atrophy in her left eye. In follow-up, the defect widened and subsequently developed into a focal choroidal excavation. Over the next 8 years, serial optical coherence tomography imaging illustrated the conversion of the focal choroidal excavation from conforming subtype into non-conforming subtype with eventual macular hole formation.
Conclusions And Importance:
The long-term follow-up of a patient with serial imaging highlights the potential dynamic nature of focal choroidal excavation in ABCA4-related retinopathy. Progressive retinal degeneration may influence focal choroidal excavation morphology and may promote macular hole formation.
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