Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum: 3D biodegradable shape changing composite scaffold with programmable porous structures for bone engineering (2022<i>Biomed. Mater.</i>17065022).

Biomedical materials (Bristol, England)·2023
Same author

Sustainable Approach for the Synthesis of a Semicrystalline Polymer with a Reversible Shape-Memory Effect.

ACS macro letters·2023
Same author

A Multiple Remotely Controlled Platform from Recyclable Polyurethane Composite Network with Shape-Memory Effect and Self-Healing Ability.

Small (Weinheim an der Bergstrasse, Germany)·2022
Same author

Enhanced biomineralization of shape memory composite scaffolds from citrate functionalized amorphous calcium phosphate for bone repair.

Journal of materials chemistry. B·2021
Same author

Biomimetic scaffolds with programmable pore structures for minimum invasive bone repair.

Nanoscale·2021
Same author

Biomimetic Polyurethane 3D Scaffolds Based on Polytetrahydrofuran Glycol and Polyethylene Glycol for Soft Tissue Engineering.

Polymers·2020
Same journal

A review on assessment of advances in polymers and their hybrid nanosystem for leukaemia theranostics applications.

Biomedical materials (Bristol, England)·2026
Same journal

Controllable preparation of magnesium-hybridized PLA-PEG-PLA porous microspheres with anti-inflammatory function.

Biomedical materials (Bristol, England)·2026
Same journal

Core-shell fibrous threads loaded with VEGF plasmid polyplexes for sustained, threshold-guided gene delivery.

Biomedical materials (Bristol, England)·2026
Same journal

3-Layer lung cancer invasion model for evaluating MMP-targeted anti-metastatic therapeutics.

Biomedical materials (Bristol, England)·2026
Same journal

Enhancement of type H vessels in bone repair of rat tibial defects treated with stromal vascular fraction-collagen sponge composites.

Biomedical materials (Bristol, England)·2026
Same journal

Emulsion-based synthesis of polycaprolactone/bioactive glass 45S5 microparticles for bone regeneration applications.

Biomedical materials (Bristol, England)·2026
See all related articles

Related Experiment Video

Updated: Aug 20, 2025

Novel Process for 3D Printing Decellularized Matrices
08:14

Novel Process for 3D Printing Decellularized Matrices

Published on: January 7, 2019

7.2K

3D biodegradable shape changing composite scaffold with programmable porous structures for bone engineering.

Xiaohu Chen1, Zuoxun Huang1, Qing Yang1

  • 1College of Materials, Chemistry & Chemical Engineering, Chengdu University of Technology, Chengdu 610059, Sichuan, People's Republic of China.

Biomedical Materials (Bristol, England)
|November 17, 2022
PubMed
Summary
This summary is machine-generated.

This study created a novel, shape-changing polyurethane scaffold using polycaprolactone and polyethylene glycol. The hydroxyapatite-filled material shows excellent biocompatibility and osteoconductivity for bone defect repair.

Keywords:
3D scaffoldsbiocompatibilityhydroxyapatitepolyurethaneshape changing behavior

More Related Videos

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
10:19

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

2.0K
Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

12.7K

Related Experiment Videos

Last Updated: Aug 20, 2025

Novel Process for 3D Printing Decellularized Matrices
08:14

Novel Process for 3D Printing Decellularized Matrices

Published on: January 7, 2019

7.2K
Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
10:19

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

2.0K
Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

12.7K

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Tissue Engineering

Background:

  • Development of advanced scaffolds for bone defect regeneration is crucial.
  • Biodegradable polymers offer potential for temporary bone support.
  • Incorporating osteoconductive materials can enhance bone healing.

Purpose of the Study:

  • To synthesize a biodegradable, shape-memory polyurethane scaffold.
  • To investigate the effect of hydroxyapatite (HA) on scaffold properties.
  • To evaluate the scaffold's suitability for bone defect implantation.

Main Methods:

  • Sequential in-situ foaming, salt leaching, and freeze-drying processes.
  • Incorporation of hydroxyapatite (HA) into a polycaprolactone and polyethylene glycol matrix.
  • Characterization using Infrared spectroscopy, SEM, XRD, DSC, and bending tests.
  • In vitro mineralization and in vivo biocompatibility assessments.

Main Results:

  • Successful synthesis of a biodegradable composite porous polyurethane scaffold.
  • HA addition decreased porosity, increased pore size, and lowered melting point near body temperature.
  • PUHA20 exhibited excellent shape memory performance (fixity >98.9%, recovery >96.2%).
  • Scaffold demonstrated good osteoconductivity and in vivo biocompatibility.

Conclusions:

  • The developed HA-polyurethane scaffold possesses responsive shape-changing capabilities.
  • The material shows promising osteoconductivity and biocompatibility for bone regeneration.
  • This scaffold is a viable candidate for treating bone defects.