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Updated: Aug 20, 2025

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
Published on: September 19, 2013
In through the Out Exit: the Role of the Exocyst in Listeria monocytogenes Cell Entry
1Instituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj," Facultad de Bioquímica, Química y Farmacia, San Miguel de Tucumán, Argentina.
Abstract:
The intracellular pathogen Listeria monocytogenes is one of the leading causes of death from foodborne illness in the United States. Internalin A is the key surface protein that drives Listeria uptake by epithelial cells expressing E-cadherin. G. C. Gyanwali, T. U. B. Herath, A. Gianfelice, and K. Ireton (Infect Immun 90:e00326-22, 2022, https://doi.org/10.1128/iai.00326-22) unravel the close relationship between internalin A and the exocyst, adding another layer of complexity to the bacterial internalization process.
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