Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

929
Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
929
Variables Affecting Phosphorescence and Fluorescence01:26

Variables Affecting Phosphorescence and Fluorescence

572
Fluorescence and phosphorescence are essential phenomena in fields like analytical chemistry, biological imaging, and materials science, where they detect molecular properties and visualize cellular structures. Understanding the variables that influence these luminescent behaviors is crucial for maximizing accuracy and efficiency in their applications. These variables can broadly be grouped into chemical structure, solvent properties, and external conditions, each playing a distinct role in...
572
Carbon Skeletons01:12

Carbon Skeletons

108.1K
Life on Earth is carbon-based, as all macromolecules that make up living organisms contain carbon atoms. All organic compounds have a carbon backbone. Each carbon atom is tetravalent and can bond with four other atoms, making it an extraordinarily flexible component of biological molecules. Because carbon’s valence electrons are stable, it rarely becomes an ion. As the carbon chain increases in length, structural modifications such as ring structures, double bonds, and branching side...
108.1K
Aromatic Hydrocarbon Cations: Structural Overview01:18

Aromatic Hydrocarbon Cations: Structural Overview

2.9K
Cycloheptatriene is a neutral monocyclic unsaturated hydrocarbon that consists of an odd number of carbon atoms and an intervening sp3 carbon in the ring. The three double bonds in the ring correspond to 6 π electrons, which is a Huckel number, and therefore satisfies the criteria of 4n + 2 π electrons. However, the intervening sp3 carbon disrupts the continuous overlap of p orbitals. As a result, cycloheptatriene is not aromatic.
Removing one hydrogen from the intervening CH2 group...
2.9K
Properties of Organometallic Compounds01:23

Properties of Organometallic Compounds

1.1K
Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.
1.1K
Cycloaddition Reactions: MO Requirements for Photochemical Activation01:12

Cycloaddition Reactions: MO Requirements for Photochemical Activation

2.2K
Some cycloaddition reactions are activated by heat, while others are initiated by light. For example, a [2 + 2] cycloaddition between two ethylene molecules occurs only in the presence of light. It is photochemically allowed but thermally forbidden.
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a quadruple-conjugated carbon dot nanomodel for targeted glioma therapy.

Communications chemistry·2026
Same author

Prospect in Alzheimer's disease integrative therapy targeting both amyloid-beta and tau.

Neural regeneration research·2025
Same author

Cell-Driven Encapsulation of Chlorophyllin-Based Carbon Dots within Exosomes for Enhanced Photodynamic Therapy: miRNA Profiling Reveals Mechanistic Insights.

ACS applied materials & interfaces·2025
Same author

Rapid mapping of spinal and supraspinal connectome <i>via</i> self-targeting glucose-based carbon dots.

Nanoscale·2025
Same author

An Electrochemical Dopamine Assay with Cobalt Oxide Palatinose Carbon Dots.

Molecules (Basel, Switzerland)·2025
Same author

Investigating the Significances of Thiol Functionalities in SARS-CoV-2 Using Carbon Dots for Viral Inhibition.

ACS applied materials & interfaces·2024

Related Experiment Video

Updated: Aug 20, 2025

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.6K

Structure-Property-Activity Relationships in Carbon Dots.

Yiqun Zhou1,2,3, Wei Zhang1, Roger M Leblanc1

  • 1Department of Chemistry, University of Miami, Coral Gables, Florida 33146, United States.

The Journal of Physical Chemistry. B
|November 17, 2022
PubMed
Summary

Carbon dots (CDs) are versatile nanomaterials with diverse applications. Understanding their structure-property-activity relationships is key to developing advanced carbon-based materials for fields like nanomedicine and photochemistry.

More Related Videos

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering
09:12

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering

Published on: June 1, 2016

9.2K
Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production
08:40

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Published on: December 6, 2021

3.6K

Related Experiment Videos

Last Updated: Aug 20, 2025

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.6K
Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering
09:12

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering

Published on: June 1, 2016

9.2K
Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production
08:40

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Published on: December 6, 2021

3.6K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Chemistry

Background:

  • Carbon dots (CDs) are highly versatile nanomaterials discovered in the 21st century.
  • CDs exhibit numerous properties, enabling diverse applications.
  • Recent research explores CDs' fractionalization and assembly, revealing their complex nature and potential as building blocks.

Purpose of the Study:

  • To highlight the crucial structure-property-activity relationships in carbon dots.
  • To summarize recent advancements in CD fractionalization and assembly.
  • To provide a forward-looking perspective on CD development and applications.

Main Methods:

  • Review and synthesis of existing research on carbon dots.
  • Analysis of structure-property-activity relationships in CDs.
  • Summary of studies on CD fractionalization and assembly.

Main Results:

  • Carbon dots are a heterogeneous mixture and effective building blocks for larger carbon materials.
  • Established structure-property-activity relationships are vital for predicting CD behavior.
  • Controllability over CDs enables the development of materials with tailored properties.

Conclusions:

  • Carbon dots have evolved significantly since their discovery, with ongoing research expanding their potential.
  • Understanding structure-property-activity relationships and leveraging the building-block nature of CDs can guide the creation of novel carbon-based materials.
  • This approach minimizes trial-and-error in materials development, benefiting materials science and chemistry.