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Published on: May 26, 2023
Midterm outcomes of endovascular treatment for infected aortic aneurysms: Single center experience
Veera Suwanruangsri1, Surakiat Bokerd1, Wanchai Chinchalongporn1
1Division of Vascular Surgery, Department of Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand.
Objective:
The standard treatment of infected aortic aneurysms is open surgical repair but mortality rates remain high with the common cause of death being sepsis. Endovascular treatment of infected aortic aneurysms is another option and here we report the midterm outcomes of endovascular treatment for infected aortic aneurysms.
Methods:
Thirty-four patients with infected aortic aneurysms underwent endovascular and hybrid repair between December 2012 and June 2021. The patients were evaluated for early and midterm outcomes including postoperative mortality, morbidity, recurrent aortic infection, and midterm survival.
Results:
There were 34 patients who presented with infected aortic aneurysms with a mean age of 66.7 years (range, 26-89). Most of the patients presented with abdominal pain (94.1%) and fever (50.0%). The rate of positive blood culture for organisms was 32.4%. Salmonella was the most common organism. The procedures for treatment were endovascular repair using straight endograft, aorto-uni-iliac (AUI) endograft, bifurcated endograft, and thoracic endograft. Other procedures were endovascular repair with sandwich technique, chimney or periscope technique, and hybrid operation. The rate of in-hospital mortality and morbidity were 11.8% and 17.6%, respectively. Mean follow-up time was 21 months (range, 1-70). During the follow-up period, 7 (23.3%) patients had recurrent infection of aortic aneurysms and 5 patients required reoperation. Four patients died from septicemia and one patient died from cardiac disease. Male patients were more likely to have recurrent infection compared to females. The cumulative survival at 1 year and 2 years were 86.3% and 80.5%, respectively.
Conclusion:
In this retrospective review of the endovascular treatment in the patients who presented with infected aortic aneurysms showed acceptable early and midterm outcomes.
Insights
Endovascular repair of infected aortic aneurysms offers acceptable midterm outcomes. This study evaluated 34 patients, showing manageable mortality and morbidity, but highlighted the risk of recurrent infection, especially in males.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Medical Device Technology
Background:
- Infected aortic aneurysms (IAAs) pose a significant challenge with high mortality from sepsis following standard open surgical repair.
- Endovascular treatment presents an alternative approach for managing IAAs, aiming to reduce perioperative risks.
Purpose of the Study:
- To report the midterm outcomes of endovascular and hybrid repair for infected aortic aneurysms.
- To evaluate early and midterm results including mortality, morbidity, and recurrent infection rates.
Main Methods:
- A retrospective review of 34 patients with IAAs treated between December 2012 and June 2021.
- Procedures included various endovascular techniques (straight, AUI, bifurcated, thoracic endografts, sandwich, chimney/periscope) and hybrid operations.
- Outcomes assessed included in-hospital mortality, morbidity, reoperation rates, recurrent infection, and survival.
Main Results:
- The study included 34 patients (mean age 66.7 years) with IAAs, commonly presenting with abdominal pain and fever. Salmonella was the most frequent organism identified.
- In-hospital mortality was 11.8% and morbidity was 17.6%. Over a mean follow-up of 21 months, 23.3% experienced recurrent infection, with 5 patients requiring reoperation.
- Cumulative survival at 1 and 2 years was 86.3% and 80.5%, respectively. Male patients showed a higher likelihood of recurrent infection.
Conclusions:
- Endovascular treatment for infected aortic aneurysms demonstrates acceptable early and midterm outcomes.
- While effective, the risk of recurrent infection necessitates ongoing surveillance and management strategies.
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