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Related Concept Videos

Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

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Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
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Peripheral Artery Disease V: Postoperative Nursing Management01:23

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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
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Related Experiment Video

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External Cephalic Version: Is it an Effective and Safe Procedure?
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Acute thrombocytopenia during cesarean section.

X Yang1, Q Xia2, J Wang1

  • 1Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Xinshi District, Xinjiang Province, China.

International Journal of Obstetric Anesthesia
|November 17, 2022
PubMed
Summary

A healthy woman developed severe thrombocytopenia during a cesarean section, likely due to the antibiotic cefoxitin. This case highlights a rare but serious adverse drug reaction to cefoxitin in obstetric anesthesia.

Keywords:
Acute thrombocytopeniaCefoxitinCesarean sectionDrug reactionSpinal anesthesia

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Area of Science:

  • Anesthesiology
  • Pharmacology
  • Obstetrics

Background:

  • Combined spinal-epidural anesthesia is frequently used for cesarean sections.
  • Surgical site infection prophylaxis is standard in cesarean deliveries.
  • Cefoxitin is a commonly used antibiotic for surgical prophylaxis.

Observation:

  • A 29-year-old parturient presented with a normal pre-operative platelet count.
  • The patient received combined spinal-epidural anesthesia for a cesarean section.
  • Sudden intra-operative onset of severe thrombocytopenia (3 × 10^9/L) occurred.

Findings:

  • The severe thrombocytopenia was temporally associated with cefoxitin administration.
  • The event was likely an adverse drug reaction to cefoxitin.
  • This represents a rare complication of cefoxitin use.

Implications:

  • Clinicians should be aware of the potential for cefoxitin-induced thrombocytopenia in obstetric patients.
  • Monitoring of platelet counts may be warranted in patients receiving cefoxitin, especially those undergoing anesthesia.
  • Alternative antibiotics with a lower risk profile for thrombocytopenia should be considered in susceptible individuals.