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Maternal pre-pregnancy anemia and childhood anemia in Indonesia: a risk assessment using a population-based
Fadila Wirawan1, Dieta Nurrika2
1Department of Public Health Nutrition, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
Insights
Maternal anemia before pregnancy significantly increases the risk of anemia in children under five. Focusing on pre-conception maternal health is crucial for preventing childhood anemia and improving child health outcomes.
Area of Science:
- Public Health
- Pediatric Nutrition
- Maternal Health
Background:
- Childhood anemia under five is a significant public health concern with long-term detrimental effects.
- Preventing childhood anemia requires a focus on maternal health during the pre-pregnancy phase.
- Early identification and intervention for maternal anemia are critical for child health.
Purpose of the Study:
- To investigate the association between maternal pre-pregnancy anemia and the risk of anemia in children under five years of age.
- To assess the independent risk factors for childhood anemia related to maternal pre-pregnancy health status.
- To inform public health strategies for anemia prevention through maternal health initiatives.
Main Methods:
- A cohort study utilizing data from the 2007 and 2014 Indonesian Family Life Surveys (IFLS).
- Inclusion of non-pregnant women and their children under five, with anemia status determined by hemoglobin levels.
- Statistical analysis using Mantel-Haenszel adjusted relative risks (aRRs) with risk stratification.
Main Results:
- Mothers with pre-pregnancy anemia had a 1.71-fold higher risk of having an anemic child compared to those without anemia.
- Maternal pre-pregnancy anemia remained an independent risk factor for childhood anemia in specific subgroups.
- Increased risk observed in children who were breastfed, received water before six months, or had mothers with normal/underweight BMI or no current anemia.
Conclusions:
- Pre-pregnancy anemia is a significant predictor of anemia in young children.
- Public health interventions should prioritize pre-conception maternal health to reduce maternal and child morbidity.
- Strengthening maternal health programs before conception is essential for preventing childhood anemia.
Objectives:
Anemia in children under 5 years of age is often overlooked despite its detrimental effects. The public health approach to anemia prevention includes the maternal pre-pregnancy phase. This study investigated the association between pre-pregnancy anemia and the risk of anemia in children under 5 years of age.
Methods:
This cohort study included non-pregnant women from the 2007 Indonesian Family Life Survey (IFLS) and their children under 5 in the 2014 IFLS. The anemia status of mothers and children was determined based on hemoglobin (Hb) levels using Hemocue. Mantel-Haenszel adjusted relative risks (aRRs), including risk stratification by covariates, were used for the final risk assessment.
Results:
In total, 637 children in the 2014 IFLS were included. The risk of having a child with anemia was 1.71-fold higher in women with pre-pregnancy anemia than in women without pre-pregnancy anemia (aRR, 1.71; 95% confidence interval [CI], 1.03 to 2.85). After risk stratification based on potential confounding variables, maternal pre-pregnancy anemia remained an independent risk factor for anemia in children who still breastfed at the time of data collection (relative risk [RR], 2.11; 95% CI, 1.16 to 3.86), in children who were given water earlier than 6 months of age (RR, 2.08; 95% CI, 1.20 to 3.61), in children of mothers with a normal or underweight pre-pregnancy body mass index (RR, 1.94; 95% CI, 1.20 to 3.14), and in children of mothers without current anemia (RR, 2.20; 95% CI, 1.21 to 3.99).
Conclusions:
Pre-pregnancy anemia increased the risk of childhood anemia. A public health approach emphasizing pre-conception maternal health would enable better maternal and child morbidity risk prevention.
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