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Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence

Maharshi Patel1, Twinkle Pawar2, Sachin Agrawal2

  • 1Department of Medicine, Jawaharlal Nehru Medical College, Wardha, IND.

Cureus
|November 18, 2022
PubMed

Endothelial cell injury, intravascular platelet-fibrin thrombi, and vascular damage are found in hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). The two disorders frequently manifest independently and are the important causes of acute renal damage. Acute kidney injury developed in our patient after blood transfusion and later on, the patient developed neurological complications. The patient was managed symptomatically and conservatively. Plasmapheresis and corticosteroid administration showed improved results.

Keywords:
acute kidney injuryendothelialintravascularplasmapheresisthrombi

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