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Related Experiment Video

Updated: Aug 20, 2025

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst
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Rathke's Cleft Cyst Abscess with a Very Unusual Course.

Amy Coulden1,2,3, Joshua Pepper4, Agata Juszczak5

  • 1Department of Endocrinology, Queen Elizabeth Hospital, Birmingham, United Kingdom.

Asian Journal of Neurosurgery
|November 18, 2022
PubMed
Summary

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Evaluation of differences in presentation and postoperative outcomes after adrenalectomy for pheochromocytoma according to age.

Endocrine connections·2026
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Journal of neurosurgery. Case lessons·2026
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Referral to Definitive Surgical Treatment in Cushing's Syndrome - An Odyssey That Requires Attention.

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Percentage signal recovery plus relative cerebral blood volume: a practical dual-parameter strategy for differentiating post-stereotactic radiosurgery tumour progression from radiation necrosis in brain metastases.

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Pituitary·2026

Infected Rathke's cleft cysts (RCC) are rare. This case details an infected RCC with intracranial abscesses, successfully treated with antibiotics, highlighting a unique presentation of this rare condition.

Area of Science:

  • Neuroendocrinology
  • Neurosurgery
  • Infectious Diseases

Background:

  • Rathke's cleft cysts (RCC) are congenital remnants of the Rathke's pouch, typically located in the pituitary region.
  • Infected RCCs are exceptionally rare, with limited documented cases in medical literature.
  • Intracranial extension of abscesses from pituitary region lesions is uncommon.

Observation:

  • A 31-year-old male presented with headaches, visual disturbances, and hypopituitarism.
  • MRI revealed ring-enhancing cystic lesions with suprasellar and intraparenchymal extension, mimicking a high-grade glioma.
  • Endoscopic transsphenoidal biopsy identified Staphylococcus aureus in the pituitary fossa, confirming an infected RCC with abscess extension.

Findings:

  • The patient was diagnosed with an infected Rathke's cleft cyst with significant intracranial spread.
Keywords:
Rathke's cleft cystpituitary abscesstransphenoidal surgery

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  • Treatment involved a prolonged course of intravenous antibiotics.
  • Resolution of the infection led to improvement in the patient's visual symptoms and overall condition.

    • Implications:

    • This case underscores the importance of considering infectious etiologies, such as infected RCC, in the differential diagnosis of sellar/suprasellar masses, even with atypical imaging findings.
    • Prompt diagnosis and appropriate antibiotic therapy are crucial for managing infected RCCs and preventing complications.
    • The unique intracranial extension of the abscess highlights the potential morbidity associated with this rare condition.