Chronic non-communicable diseases: Hainan prospective cohort study
Xingbo Gu1, Liuting Lin2,3, Chanjuan Zhao1
1Department of Biostatistics, International School of Public Health and One Health, Hainan Medical University, Haikou, Hainan, China.
Insights
The Hainan Cohort study tracks non-communicable diseases in China. Baseline data reveal high prevalence of hypertension and diabetes, informing future public health strategies.
Area of Science:
- Epidemiology
- Public Health
- Chronic Disease Research
Background:
- The Hainan Cohort study is a large-scale epidemiological initiative in China.
- It aims to understand the prevalence and risk factors of non-communicable diseases (NCDs) within a community setting.
Purpose of the Study:
- To investigate the incidence, morbidity, and mortality of NCDs.
- To identify key risk factors associated with these diseases in the Hainan population.
Main Methods:
- A multistage cluster random-sampling method was employed to recruit participants.
- Baseline data collection involved questionnaires, physical examinations, biological sample collection, and environmental data acquisition.
- The study enrolled 14,443 participants aged 35-74 years with a high participation rate of 90.1%.
Main Results:
- The crude prevalence of hypertension was 37.1%, and diabetes was 8.6%.
- Other prevalent conditions included coronary heart disease (9.2%) and metabolic syndrome (14.5%).
- The cohort comprises a well-educated population with a mean age of 48.8 years, and 51.8% are male.
Conclusions:
- The Hainan Cohort provides valuable baseline data for NCD research in China.
- Long-term monitoring will offer insights into disease progression and mortality trends.
- Findings will guide targeted public health interventions and prevention strategies.
Purpose:
The Hainan Cohort was established to investigate the incidence, morbidity and mortality of non-communicable diseases and their risk factors in the community population.
Participants:
The baseline investigation of the Hainan Cohort study was initiated in five main areas of Hainan, China, from June 2018 to October 2020. A multistage cluster random-sampling method was used to obtain samples from the general population. Baseline assessments included a questionnaire survey, physical examination, blood and urine sample collection, and laboratory measurements, and outdoor environmental data were obtained.
Findings To Data:
A total of 14 443 participants aged 35-74 years were recruited at baseline, with a participation rate of 90.1%. The mean age of the participants was 48.8 years; 51.8% were men, and 83.7% had a secondary school or higher education. The crude prevalence of diabetes, coronary heart disease, stroke, hypertension, hyperuricaemia, chronic bronchitis, pulmonary tuberculosis, asthma, cancer, chronic hepatitis and metabolic syndrome were 8.6%, 9.2%, 2.0%, 37.1%, 7.1%, 2.3%, 1.4%, 2.1%, 4.1%, 2.2% and 14.5%, respectively.
Future Plans:
The Hainan Cohort is a dynamic cohort with no end date. All participants will be monitored annually for cause-specific mortality and morbidity until death. Long-term follow-up will be conducted every 5 years. The baseline population is considered to expand in the next wave of follow-up, depending on the availability of funding support.
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