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Risk factors of acute cerebral infarction in patients with primary hypertension

Deliang Zheng1, Xinmiao Li2, Yongping Fu2

  • 1Department of Laboratory, People's Hospital of Honghuagang District, 134 Linjiapo Road, Zunyi City, 563000, Guizhou Province, China. 877677121@qq.com.

Irish Journal of Medical Science
|November 18, 2022
PubMed

Insights

Diabetes mellitus is a significant risk factor for acute cerebral infarction (ACI) in patients with primary hypertension. Poor blood glucose control in diabetes may increase the risk of developing ACI.

Area of Science:

  • Neurology
  • Cardiology
  • Endocrinology

Background:

  • Primary hypertension is a major risk factor for cardiovascular diseases.
  • Acute cerebral infarction (ACI) is a serious complication of hypertension.
  • Understanding risk factors for ACI in hypertensive patients is crucial for prevention.

Purpose of the Study:

  • To identify risk factors for acute cerebral infarction (ACI) in patients with primary hypertension.
  • To investigate the association between diabetes mellitus and ACI in hypertensive individuals.

Main Methods:

  • Retrospective study of hypertensive patients with ACI (n=300) and without ACI (control group, n=117).
  • Data collected included demographics, lifestyle factors, laboratory results, and comorbidities.
  • Statistical analysis was performed to identify significant risk factors.

Main Results:

  • Patients with hypertensive ACI showed higher levels of glycosylated hemoglobin, D-dimer, and FDPs compared to controls.
  • Diabetes mellitus was significantly associated with ACI in patients with primary hypertension (OR=1.452, P=0.004).

Conclusions:

  • Diabetes mellitus is an independent risk factor for acute cerebral infarction in patients with primary hypertension.
  • Poor glycemic control in pre-existing diabetes may contribute to the development of ACI.
Abstract

Keywords:
Acute cerebral infarctionDiabetes mellitusHypertensionRisk factors

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