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Updated: Aug 20, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

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Dynamics and mechanistic interpretations of nonribosomal peptide synthetase cyclization domains

Andrew D Gnann1, Kenneth Marincin2, Dominique P Frueh2

  • 1Department of Chemistry, University of Massachusetts Boston, Boston, MA, 02125, USA.

Current Opinion in Chemical Biology
|November 19, 2022
PubMed

Keywords:
AllosteryBioengineeringCyclodehydrationHeterocyclePantetheineProtein–protein interactions

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